Results 41 to 50 of about 148,841 (263)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Assessing local determinants of neural tube defects in the Heshun Region, Shanxi Province, China
BMC Public Health, 2010 Background Neural tube defect (NTD) prevalence in northern China is among the highest worldwide. Dealing with the NTD situation is ranked as the number one task in China's scientific development plan in population and health field for the next decade ...
Liao Yi-Lan +5 more
doaj +1 more source
Statistical Reconstruction of the Antarctic Oscillation Index Based on Multiple Proxies
Atmospheric and Oceanic Science Letters, 2010 AbstractBased on multiple proxies from the Southern Hemisphere, an austral summer (December-January-February: DJF) Antarctic Oscillation Index (AAO) since 1500 A.D. was reconstructed with a focus on interannual to interdecadal variability (
Zhang Zi-Yin +4 more
openaire +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Children and caregiver proxy quality of life from peanut oral immunotherapy trials
Clinical and Translational Allergy, 2022 Background Health‐related quality of life (HRQoL) is significantly and substantially reduced in individuals with peanut allergy due to many factors associated with unanticipated or potentially fatal reactions. Further insight on the impact of peanut oral
Audrey Dunn Galvin +9 more
doaj +1 more source
Ensemble Statistics Accessed through Proxies: Range Heuristic and Dependence on Low-Level Properties in Variability Discrimination [PDF]
Journal of Vision, 2018 People can quickly and accurately compute not only the mean size of a set of items but also the size variability of the items. However, it remains unknown how these statistics are estimated. Here we show that neither parallel access to all items nor random subsampling of just a few items is sufficient to explain participants' estimations of size ...
Brady , Timothy +2 more
openaire +5 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Geology, Ecology, and Landscapes, 2020 This study presents the characterisation of grain size dynamics within an estuarine environment through statistical summarisation of grain size distribution and multivariate statistics.
Temitope D. Timothy Oyedotun
doaj +1 more source
Quantitative Science Studies, 2021 This study compares publisher ratings to the visibility and impact of individual books, based on a 2017 data set from three Nordic performance-based research funding systems (PRFS) (Denmark, Norway, and Finland). Although there are Journal Impact Factors
Alesia A. Zuccala +6 more
doaj +1 more source