Results 21 to 30 of about 1,761,182 (182)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Cimentando un proyecto de investigación: la revisión de literatura [PDF]
, 2004 En este capítulo se reflexiona sobre la importancia de las búsquedas bibliográficas en la organización y desarrollo de un proyecto de investigación en didáctica de las matemáticas.
Gutiérrez, Ángel, Maz, Alexander
core
Color Routing and Beam Steering of Single‐Molecule Emission with a Spherical Silicon Nanoantenna
Advanced Functional Materials, EarlyView.We experimentally demonstrate broadband directional emission from single molecules using a single spherical silicon nanoparticle assembled via DNA origami. By varying nanoparticle (NP) size and emitter position, we achieve unidirectional emission, beam steering, and color routing at the nanoscale, revealing modal interference as the underlying ...
María Sanz‐Paz +9 more
wiley +1 more source
Derechos fundamentales y dignidad humana [PDF]
, 2011 Proyecto Consolider-Ingenio 2010 “El tiempo de los derechos” CSD2008-00007; Proyecto de Investigación “Historia de los derechos fundamentales. Siglo XX” (DER-2008-03941/JURI); Plan Nacional de Investigación Científica, Desarrollo e Innovación ...
Ansuátegui Roig, Francisco Javier
core +5 more sources
Revista Digital de Investigación en Docencia Universitaria, 2018 -
Carlos Huayanay-Espinoza +5 more
doaj +1 more source
Advanced Intelligent Systems, EarlyView.This study presents a multitask strategy for plastic cleanup with autonomous surface vehicles, combining exploration and cleaning phases. A two‐headed Deep Q‐Network shared by all agents is traineded via multiobjective reinforcement learning, producing a Pareto front of trade‐offs.
Dame Seck +4 more
wiley +1 more source
Medicamentos biosimilares en Colombia: una revisión desde el consumo informado
Revista Ciencias de la Salud, 2018 Introducción: este artículo presenta un análisis sobre medicamentos biosimilares en Colombia con miras a establecer si existe un consumo informado respecto de estos fármacos, teniendo en cuenta la calidad y cantidad de información que circula en ...
Diana Rocío Bernal-Camargo +2 more
doaj +1 more source
Miscelánea Comillas, 2022 Este trabajo describe los aspectos fundamentales que debe contener un proyecto de investigación social, que pueda orientar a estudiantes y futuros investigadores.
Carmen Meneses-Falcón
doaj +1 more source
The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, EarlyView.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Exogenous application of GnRH after fixed-time artificial insemination (FTAI) and its effect on serum progesterone levels and pregnancy rate in primiparous dairy cows at high altitude environments [PDF]
SPERMOVA, 2016 The aim of the present study was to determine the effect of the exogenous application of gonadotropin-releasing hormone (GnRH) on day 4, 8 and 12 after fixed-time artificial insemination (post-FTAI) in order to evaluate its influence on serum ...
Gutiérrez-Reinoso MA +2 more
doaj +3 more sources