Results 61 to 70 of about 22,337 (206)

Underexplored Ligand‐Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite   +10 more
wiley   +1 more source

The power of many: when genetics met yeasts and high‐throughput

open access: yesBiological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Sistema de identificación para filtros activos de potencia

open access: yesMaskana, 2016
RESUMEN El presente artículo es un estudio de un sistema de identificación, aplicado a filtros activos de potencia, utilizando convertidores multinivel.
Felipe Peña   +2 more
doaj  

Pastwomen: un proyecto de investigación feminista colaborativo

open access: diamond, 2023
Antonia García Luque   +2 more
openalex   +2 more sources

Comparative Analysis of Correlative Modeling Methods in Predicting North American Bird Abundance

open access: yesEcology and Evolution, Volume 16, Issue 8, August 2026.
This study compares nine ecological niche model (ENM) methods to predict North American bird abundance and finds positive correlations between environmental suitability and abundance. Results highlight the potential of ENMs for abundance inference, with newer methods showing good performance and demonstrating that simpler data inputs can be effective ...
Jazmín Escobar‐Luján   +3 more
wiley   +1 more source

Resmetirom Ameliorates Fibrogenesis in Hepatic Stellate Cells via Thyroid Hormone Receptor Alpha‐Fatty‐Acid Amide Hydrolase 1 Signaling Pathway

open access: yesMedComm, Volume 7, Issue 8, August 2026.
1. Resmetirom attenuates the activation of HSCs induced in in vitro and in vivo models. 2. Resmetirom attenuates the activation of HSCs through its specific action on the thyroid hormone receptor alpha. 3. Resmetirom requires fatty‐acid amide hydrolase 1 to reduce HSC activation. ABSTRACT Resmetirom is a liver‐directed, thyroid hormone receptor β (THRβ)
Eva Novoa   +17 more
wiley   +1 more source

Cementum Attachment Protein‐Derived Peptides Modulate Brushite and Calcium Oxalate Crystallization In Vitro

open access: yesJournal of Peptide Science, Volume 32, Issue 8, August 2026.
Cementum attachment protein‐derived peptides adsorb to specific crystallographic faces of brushite and calcium oxalate, blocking calcium deposition. This phosphorylation‐enhanced modulation alters crystal growth under conditions in vitro, leading to the formation of irregular brushite crystals and rosette‐like calcium oxalate morphologies.
Alberto Mimila‐Cortes   +9 more
wiley   +1 more source

Informe final proyecto de investigación FODEIN. Valores percibidos por los consumidores de los estratos socioeconómicos 2 y 3 de los formatos “Discounter” y las Tiendas de Barrio en la ciudad de Bogotá [PDF]

open access: hybrid, 2020
Riveros Polonia Gustavo   +6 more
openalex   +1 more source

Random Friend Trees

open access: yesRandom Structures &Algorithms, Volume 69, Issue 1, August 2026.
ABSTRACT We study a random recursive tree model featuring complete redirection called the random friend tree and introduced by Saramäki and Kaski (2004). Vertices are attached sequentially, one by one, by selecting an existing target vertex and connecting to one of its neighbours (or friends), chosen uniformly at random.
Louigi Addario‐Berry   +5 more
wiley   +1 more source

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