Results 241 to 250 of about 159,476 (341)

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu   +7 more
wiley   +1 more source

Doppel as an early‐stage biomarker promoting EMT and dissemination in ovarian cancers

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1755-1768, 15 March 2026.
What's new? Existing biomarkers for ovarian cancer (OC) lack the sensitivity and specificity needed to consistently distinguish the malignancy from non‐ovarian influences and other cancers. Here, the authors explored the ability of the prion‐like protein Doppel, normally found in the male testes, to detect OC.
Zulfikar Azam   +18 more
wiley   +1 more source

Advancing prion diagnostics: full-length human E200K RT-QuIC substrate facilitates prion detection in tear fluid and improves sensitivity in cerebrospinal fluid. [PDF]

open access: yesActa Neuropathol Commun
Correia SDS   +12 more
europepmc   +1 more source

Declining Trends in Gastrointestinal Parasitic Infections Among Nepalese School Children: A Systematic Review and Meta‐Analysis (2004–2022)

open access: yesPublic Health Challenges, Volume 5, Issue 1, March 2026.
This meta‐analysis of 25 studies (17,628 children) shows a substantial decline in gastrointestinal parasitic infections in Nepal from 43.4% to 24.2% between 2004 and 2022. Helminths (20.0%) remained more common than protozoa (9.9%), with slightly higher prevalence in urban (29.0%) than rural areas (27.9%). ABSTRACT Background Gastrointestinal parasitic
Jitendra Gautam   +8 more
wiley   +1 more source

BoGHV-4 Genotypic Diversity Shapes Inflammatory and Viral Gene Expression in Platelet-Rich Plasma-Supplemented Bovine Endometrial Cells. [PDF]

open access: yesViruses
López S   +10 more
europepmc   +1 more source

Attributional sense‐making of distrust in professional service firms: Working in a coopetitive paradox

open access: yesJournal of Occupational and Organizational Psychology, Volume 99, Issue 1, March 2026.
Abstract Distrust is an inevitable yet often overlooked feature of relationships in professional service firms (PSFs), where simultaneous demands to collaborate and compete produce a coopetitive paradox shaping everyday organizational life. Drawing on 50 in‐depth qualitative interviews using the critical incident technique, we examine how professionals
Neve Abgeller   +3 more
wiley   +1 more source

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