Results 111 to 120 of about 51,239 (287)
Precision Radiation Oncology, EarlyView.The combination of immune checkpoint inhibitors (ICIs) and radiotherapy synergistically enhances efficacy through an “antigen release‐immune activation” closed‐loop mechanism, significantly improving outcomes in solid tumors (e.g., lung cancer, melanoma).
Guiling Song +5 more
wiley +1 more source
A disproportionality analysis of FDA adverse event reporting system (FAERS) events for filgotinib.
PLoS ONEBackgroundAlthough filgotinib, a selective Janus kinase 1 inhibitor, has been increasingly applied in the treatment of inflammatory diseases, its comprehensive safety profile remains insufficiently characterized.
Yinli Shi +7 more
doaj +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
PlantsPhytophthora root rot (PRR) of chickpea (Cicer arietinum) caused by Phytophthora medicaginis is an important disease. Partial resistance to PRR is sourced from Cicer echinospermum.
Sean L. Bithell +5 more
doaj +1 more source
Sustainable Development, EarlyView.ABSTRACT Chemical engineering faces an increasing imperative to integrate sustainability principles beyond traditional economic and environmental considerations. The social dimension—encompassing impacts on human well‐being, equity, community health, labor practices, and ethical governance—represents a critical yet often underdeveloped pillar within ...
José M. R. C. A. Santos
wiley +1 more source
, 2022 Rapporto attività WP Raggi Gamma 1 Luglio – 30 Novembre ...
PITTORI, Carlotta, LUCARELLI, Fabrizio
openaire +1 more source
Structural Concrete, EarlyView.Abstract Reinforced concrete flat slabs are widely employed in contemporary architecture due to their structural efficiency and construction simplicity; however, their susceptibility to punching shear failure remains a critical design concern, particularly at slab–column connections where concentrated loads occur.
Jeovan Pereira das Virgens +4 more
wiley +1 more source
Experimental analysis of bolted connections for precast concrete walls under cyclic tensile loading
Structural Concrete, EarlyView.Abstract Dry‐bolted connections in precast wall structures simplify the assembly process and offer significant advantages in terms of construction speed and cost. In fact, the reduction of the required workmanship, compared to wet connections, makes this solution highly competitive.
Ricardo Martins +5 more
wiley +1 more source
The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li +4 more
wiley +1 more source
Role of Antimicrobial Peptides in the Pathogenesis of Atopic Dermatitis
The Journal of Dermatology, EarlyView.ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by barrier dysfunction, immune dysregulation, and microbial dysbiosis. Recent studies have highlighted the multifaceted roles of antimicrobial peptides (AMPs) both as innate defenders against microbial invasion and as regulators of immune responses and skin barrier ...
Ge Peng +9 more
wiley +1 more source