The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes +6 more
wiley +1 more source
Correlations of Glycaemic Index and Estimated Whole Blood Viscosity with Blood Cell Indices in Diabetes Mellitus Management: A Clinical Laboratory Medicine Observational Cohort Study. [PDF]
Mbah JI +4 more
europepmc +1 more source
ABSTRACT The incidence of pests and diseases seriously impacts rice production, and NLR genes play a crucial role in the regulation of immune signalling in rice. Here, we identified an NLR gene OsRGA3 that positively regulates rice resistance to brown planthopper (BPH) and rice blast disease (RBD).
Yuan Zhong +6 more
wiley +1 more source
Cardiovascular Safety Landscape of ADT in Prostate Cancer Treatment Based on Real-World Analysis. [PDF]
Wang W +7 more
europepmc +1 more source
ABSTRACT Wheat stripe rust (Puccinia striiformis f. sp. tritici, Pst) poses a catastrophic threat to global food security. While MADS‐box transcription factors regulate development and abiotic stress, their roles in plant‐pathogen immunity remain enigmatic.
Shijia Zhao +14 more
wiley +1 more source
Comparative safety profiles of spironolactone, eplerenone, and finerenone: a pharmacovigilance study based on FAERS data from 2004 to 2024. [PDF]
Ji K +8 more
europepmc +1 more source
H3K27me3‐Mediated Epigenetic Silencing of FgHMG1 Enables Fungal Host Immune Evasion
ABSTRACT Histone H3 lysine 27 trimethylation (H3K27me3) is essential for fungal pathogenicity, yet its contribution to pathogen–host interactions remains incompletely understood. Here, we profiled H3K27me3 dynamics in Fusarium graminearum during infection and identified 132 H3K27me3‐marked genes (FgHMGs).
Xiaozhen Zhao +17 more
wiley +1 more source
Proton Pump Inhibitors and Disproportionate Reporting of Acute Kidney Injury and Tubulointerstitial Nephritis: A FAERS Pharmacovigilance Study, 2020-2025. [PDF]
Alshammari TM +4 more
europepmc +1 more source
ABSTRACT As global warming continues, rising temperatures significantly alter the interactions between wheat and the stripe rust pathogen Puccinia striiformis f. sp. tritici (Pst). Utilising high‐temperature all‐stage (HTAS) resistance to Pst is a novel strategy for breeding climate and disease resilient wheat cultivars.
Yifeng Shi +6 more
wiley +1 more source

