Results 141 to 150 of about 82,842 (322)

SSDC-PRR-GAMMA-001-2022

open access: yes, 2022
Rapporto attività WP Raggi Gamma 1 Luglio – 30 Novembre ...
PITTORI, Carlotta, LUCARELLI, Fabrizio
openaire   +1 more source

Deciphering the Heterogeneity of Pulmonary Macrophages in Response to Fine Particles

open access: yesSmall, EarlyView.
This study introduces a dual‐labeled gold nanoparticle model to capture particle–responsive cells via integrating fluorescence‐activated cell sorting and single‐cell RNA sequencing. Fourteen macrophage subsets are identified with response and function heterogeneity, among which AMs_3, AMs_7, and recMacs_4 subsets show stronger phagocytic activation ...
Qing'e Shan   +11 more
wiley   +1 more source

Mannose Oligosaccharide‐Conjugated In Situ Pore‐Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

open access: yesSmall Methods, EarlyView.
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang   +9 more
wiley   +1 more source

Mechanism of RIPK3 in activation of PRRs/NLRP3 signaling pathway in macrophages induced by wear particles in aseptic joint loosening [PDF]

open access: bronze, 2020
ShiXun Li   +8 more
openalex   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li   +4 more
wiley   +1 more source

Role of Antimicrobial Peptides in the Pathogenesis of Atopic Dermatitis

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by barrier dysfunction, immune dysregulation, and microbial dysbiosis. Recent studies have highlighted the multifaceted roles of antimicrobial peptides (AMPs) both as innate defenders against microbial invasion and as regulators of immune responses and skin barrier ...
Ge Peng   +9 more
wiley   +1 more source

Genetic dissection of complete genomes of Type 2 PRRS viruses isolated in Denmark over a period of 15 years

open access: hybrid, 2013
Lise Kirstine Kvisgaard   +4 more
openalex   +1 more source

Iflaviruses in arthropods: when small is mighty

open access: yesInsect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia   +3 more
wiley   +1 more source

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