The Role of Oxidative Stress in Periodontitis
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
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The applicability of pig oral fluid in laboratory diagnostics of porcine reproductive and respiratory syndrome and its effectiveness in controlled exposure of gilts. [PDF]
Plut J, Brabec M, Štukelj M.
europepmc +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
BRCA1 deficiency induces NFκB-dependent type-I interferon signaling in fallopian tube epithelial cells. [PDF]
Madaan V, Kollara A, Spaner D, Brown TJ.
europepmc +1 more source
Autoimmunity and Periodontitis
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
Pattern recognition receptor signaling in otitis media: immune crosstalk and pathogenic mechanisms. [PDF]
Guo M +5 more
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Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
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Divergent cis-regulatory haplotypes at Tlr2 are associated with immune responsiveness. [PDF]
Nandakumar M +5 more
europepmc +1 more source
Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo +3 more
wiley +1 more source
Refractory Behavior in Plant Cells-Calcium Signaling Induced by Biotic Stress. [PDF]
Keßler MK +3 more
europepmc +1 more source

