This review examines the structural and enzymatic properties of cyclic GMP‐AMP synthase, including substrate promiscuity, homologs, and engineered variants. In addition, it evaluates potential expression systems for large‐scale enzyme production and analyzes reaction and purification strategies for the synthesis of cyclic dinucleotides to connect ...
Makram Fataeri, Katrin Rosenthal
wiley +1 more source
Horse Welfare and Natural Values on Semi-Natural and Extensive Pastures in Finland: Synergies and Trade-Offs [PDF]
In several regions in Europe, the horse is becoming a common grazer on semi-natural and cultivated grasslands, though the pasturing benefits for animals and biodiversity alike are not universally appreciated.
Herzon, Iryna +4 more
core +3 more sources
A high density SNP array for the domestic horse and extant Perissodactyla: utility for association mapping, genetic diversity, and phylogeny studies. [PDF]
An equine SNP genotyping array was developed and evaluated on a panel of samples representing 14 domestic horse breeds and 18 evolutionarily related species. More than 54,000 polymorphic SNPs provided an average inter-SNP spacing of ∼43 kb.
Molly E McCue +21 more
doaj +1 more source
ABSTRACT Aim Animal movements are a fundamental process affecting communities and ecosystems. Quantifying habitat selection across species and habitats is key for understanding how animals respond to environmental change. Currently, we lack comparative studies that examine how habitat selection varies across species traits and landscapes.
Björn H. Franke +77 more
wiley +1 more source
Collapse of the world's largest herbivores [PDF]
Large wild herbivores are crucial to ecosystems and human societies. We highlight the 74 largest terrestrial herbivore species on Earth (body mass ≥100 kg), the threats they face, their important and often overlooked ecosystem effects, and the ...
Andrade +38 more
core +3 more sources
WildWing: An open‐source, autonomous and affordable UAS for animal behaviour video monitoring
Abstract Drones have become invaluable tools for studying animal behaviour in the wild, enabling researchers to collect aerial video data of group‐living animals. However, manually piloting drones to track animal groups consistently is challenging due to complex factors such as terrain, vegetation, group spread and movement patterns. The variability in
Jenna Kline +6 more
wiley +1 more source
Vertebrate TFPI-2 C-terminal peptides exert therapeutic applications against Gram-negative infections [PDF]
Background: Tissue factor pathway inhibitor-2 (TFPI-2) is a serine protease inhibitor that exerts multiple physiological and patho-physiological activities involving the modulation of coagulation, angiogenesis, tumor invasion, and apoptosis.
Emanuel Smeds +5 more
core +2 more sources
In 2015, the Joint Directorate of State Nature Reserves «Orenburg» and «Shaitan-Tau» (FSFI «Orenburg Reserves») launched the Programme on establishing a semi-free population of the Przewalski's horse Equus ferus przewalskii in the 165 km2 Pre-Urals ...
Daniel Klich +5 more
doaj +1 more source
Capture and Anaesthesia of Wild Mongolian Equids – the Przewalski’s Horse ( Equus ferus przewalskii ) and Khulan ( E. hemionus ) [PDF]
Science-based conservation efforts in general, and wide-ranging equid conservation speci fi cally, of- ten require capture and subsequent handling of the subject animal.
Chris Walzer +5 more
doaj +1 more source
Accurate Runs of Homozygosity Estimation From Low Coverage Genome Sequences in Non‐Model Species
ABSTRACT Runs of homozygosity (ROH) are increasingly being analysed using whole genome sequences in non‐model species as a measure of inbreeding and to assess demographic history, thus providing useful information for conservation. However, most studies have used Plink for ROH inference which performs poorly when sequencing depth is below 10×, often ...
Rebecca S. Taylor +2 more
wiley +1 more source

