Results 81 to 90 of about 15,848 (137)

In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target. [PDF]

Blood Cancer Discov, 2023
Vujovic A, de Rooij L, Chahi AK, Chen HT, Yee BA, Loganathan SK, Liu L, Chan DCH, Tajik A, Tsao E, Moreira S, Joshi P, Xu J, Wong N, Balde Z, Jahangiri S, Zandi S, Aigner S, Dick JE, Minden MD, Schramek D, Yeo GW, Hope KJ.   +22 more
europepmc   +1 more source

Review of Tore Rye Andersen, Planetary Pynchon: History, Modernity, and the Anthropocene (Cambridge University Press, 2023), 228 pp.

Orbit
None
Jeff Severs
doaj   +2 more sources

“On Deleuze and Guattari’s Italian Wedding Fake Book: Pynchon, Improvisation, Social Organisation, and Assemblage”

Orbit, 2016
This article examines Pynchon’s literary invention of Deleuze and Guattari’s Italian Wedding Fake Book. Featured in his novel Vineland (1990), previous scholarship has either dismissed the reference as a throwaway joke or argued that Pynchon’s invocation
Jeeshan Gazi
doaj   +2 more sources

Similar firing rates between C57BL/6 and APP/PS1 mice.

(A) In dCA1, overall firing rates in C57BL/6 and APP/PS1 mice were not significantly different (mean ± std: C57BL/6 = 4.4 ± 5.3 Hz, APP/PS1 = 5.4 ± 7.3 Hz, p = 0.43, two-sided Wilcoxon rank-sum test, nC57BL/6 = 305 neurons, nAPP/PS1 = 180 neurons).
Udaysankar Chockanathan (18510288), Krishnan Padmanabhan (17652378)   +1 more
core   +1 more source

Identification of caspases that cleave presenilin-1 and presenilin-2 Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases

, 1999
Mutations in the presenilin (PS) genes PS1 and PS2 are involved in Alzheimer's disease (AD). Recently, apoptosis-associated cleavage of PS proteins was identified.
van Broeckhoven, Christine, van den Brande, I., van den Brande, Ilse, de Jonghe, Chris, Vanderhoeven, I., Geert van Gassen, van de Craen, Marc, van Criekinge, Wim, van de Craen, M., Vanderhoeven, Inge, Fiers, W., Declercq, W., Ilse van den Brande, Wim Declercq, Marc van de Craen, Fiers, Walter, Wim van Criekinge, Chris de Jonghe, Inge Vanderhoeven, Walter Fiers, Christine van Broeckhoven, van Gassen, Geert, Lydia Hendriks, Declercq, Wim, Vandenabeele, P., Vandenabeele, Peter, Hendriks, Lydia, van Crieckinge, W., Peter Vandenabeele   +28 more
core   +1 more source

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition. [PDF]

Elife, 2021
Colombo AV, Sadler RK, Llovera G, Singh V, Roth S, Heindl S, Sebastian Monasor L, Verhoeven A, Peters F, Parhizkar S, Kamp F, Gomez de Aguero M, MacPherson AJ, Winkler E, Herms J, Benakis C, Dichgans M, Steiner H, Giera M, Haass C, Tahirovic S, Liesz A.   +21 more
europepmc   +1 more source

Differentially expressed genes in Alzheimer's disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1. [PDF]

Brain Behav Immun Health, 2021
Li QS, De Muynck L.
europepmc   +1 more source

The ratio of APP localized in lipid rafts was higher in the CHO PS1 ΔE9 cells than in the CHO PS1 WT cells.

, 2019
The CHO PS1 WT and ΔE9 cells were homogenized with sodium carbonate buffer as described in Methods. The cell lysates were used for discontinuous sucrose density gradients.
Sungkwon Chung (71502), Tae-Wan Kim (2235994), Yoon Young Cho (838272), Myoung Kyu Park (6264629), Oh-Hoon Kwon (1847566)   +4 more
core   +1 more source

Hodges, Patricia Ann (Morgan), b. 1931 (SC 3576)

, 2020
Finding aid and scan (Click on Additional Files below) for Manuscripts Small Collection 3576. “History of Manuscript Division and Bibliography of Literary Manuscripts” by Patricia M. Hodges, Manuscript Librarian at Western Kentucky University.
Folklife Archives, Manuscripts &
core  

Expression of Presenilin 1 and 2 (PS1 and PS2) in Human and Murine Tissues

, 1996
Mutations in genes encoding related proteins, termed presenilin 1 (PS1) and presenilin 2 (PS2), are linked to the majority of cases with early-onset familial Alzheimer’s disease (FAD).
Sangram S. Sisodia, Michael K. Lee, Samuel E. Gandy, Hilda H. Slunt, Gopal Thinakaran, Mary Seeger, Grace Kim, Donald L. Price, Edward Koo, Lee J. Martin   +9 more
core   +1 more source