Results 31 to 40 of about 13,219 (262)

Energy-Preserving AVF Methods for Riesz Space-Fractional Nonlinear KGZ and KGS Equations

Fractal and Fractional, 2023
The Riesz space-fractional derivative is discretized by the Fourier pseudo-spectral (FPS) method. The Riesz space-fractional nonlinear Klein–Gordon–Zakharov (KGZ) and Klein–Gordon–Schrödinger (KGS) equations are transformed into two infinite-dimensional ...
Jianqiang Sun, Siqi Yang, Lijuan Zhang
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Pseudo-almost periodic solutions for first-order neutral differential equations

Advances in Difference Equations, 2018
In this paper, we study a class of first-order neutral differential equations with time-varying delays and coefficients. Employing the fixed point method and differential inequality techniques, easily verifiable delay-independent criteria are established
Yuehua Yu, Shuhua Gong
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Numerical solution of variable-order time fractional weakly singular partial integro-differential equations with error estimation

Mathematical Modelling and Analysis, 2020
In this paper, we apply Legendre-Laguerre functions (LLFs) and collocation method to obtain the approximate solution of variable-order time-fractional partial integro-differential equations (VO-TF-PIDEs) with the weakly singular kernel.
Haniye Dehestani, Yadollah Ordokhani, Mohsen Razzaghi   +2 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Weighted pseudo periodic solutions of neutral functional differential equations

Electronic Journal of Differential Equations, 2014
In this article, we introduced and explore the properties of two sets of functions: weighted pseudo periodic functions of class r, and weighted Stepanov-like pseudo periodic functions of class r. We show the existence and uniqueness of weighted pseudo
Zhinan Xia
doaj  

AN INVERSE PROBLEM OF RECOVERING THE RIGHT HAND SIDE OF 1D PSEUDOPARABOLIC EQUATION

Вестник КазНУ. Серия математика, механика, информатика, 2021
Inverse problems of finding the right-hand side of a partial differential equations arise when an external source is unknown or impossible to measurement, for example, the source is in a high-temperature environment or underground.
Kh. Kenzhebai
doaj   +1 more source

On the Well-Posedness for a Class of Pseudo-Differential Parabolic Equations [PDF]

Integral Equations and Operator Theory, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources