Results 21 to 30 of about 3,215 (245)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

A Remark Related Pseudo-Differential Operators on Multi-Parameter Besov-Lipschitz and Triebel-Lizorkin Spaces

open access: yesJournal of Function Spaces, 2022
Let a symbol σx,ξ belongs to the class S1,1,δ1,δ20,0 with x,ξ∈ℝn1×ℝn2 and 0≤δ1 ...
Chengdan Xu
doaj   +1 more source

On a digital approximation for pseudo‐differential operators [PDF]

open access: yesPAMM, 2017
AbstractWe introduce a concept of a discrete pseudo‐differential operator using general ideas of the theory and would like to show correlations between continuous and discrete cases. (© 2017 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Vasilyev, A., Vasilyev, V.
openaire   +2 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

On the disentanglement of Gaussian quantum states by symplectic rotations

open access: yesComptes Rendus. Mathématique, 2020
We show that every Gaussian mixed quantum state can be disentangled by conjugation with a unitary operator corresponding to a symplectic rotation via the metaplectic representation of the symplectic group.
de Gosson, Maurice A.
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Eigenvalue asymptotics for a class of multi-variable Hankel matrices

open access: yesConcrete Operators, 2023
A one-variable Hankel matrix Ha{H}_{a} is an infinite matrix Ha=[a(i+j)]i,j≥0{H}_{a}={\left[a\left(i+j)]}_{i,j\ge 0}. Similarly, for any d≥2d\ge 2, a dd-variable Hankel matrix is defined as Ha=[a(i+j)]{H}_{{\bf{a}}}=\left[{\bf{a}}\left({\bf{i}}+{\bf{j}})]
Tantalakis Christos Panagiotis
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

On the asymptotic expansion of certain plane singular integral operators

open access: yesBoundary Value Problems, 2017
We discuss the problem of the asymptotic expansion for some operators in a general theory of pseudo-differential equations on manifolds with borders. Using the distribution theory one obtains certain explicit representations for these operators.
Vladimir Vasilyev
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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