Results 211 to 220 of about 64,813 (288)

Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago   +3 more
wiley   +1 more source

Integrating polygenic and methylation risk scores for pleural mesothelioma risk stratification

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Asbestos exposure is a major risk factor for pleural mesothelioma (PM). Most asbestos‐exposed individuals do not develop PM, suggesting that it arises from a complex interplay between environmental and genetic factors. This study examined the utility of polygenic risk scores (PRS) and methylation risk scores (MRS) in incorporating genetic ...
Khadija Sana Hafeez   +26 more
wiley   +1 more source

Are Galliformes of the High Himalayas Well Protected? Identifying Conservation Priority Areas Using an Assemblage‐Level Approach 高喜马拉雅地区的鸡形目鸟类是否得到了有效保护?利用群落水平方法确定优先保护区域

open access: yesIntegrative Conservation, EarlyView.
This study investigates distribution patterns of Galliforms in the Indian Himalayas, focusing on factors influencing their occurrence, regions of high diversity and endemism, and their overlap with protected areas. Our study highlights the need for assemblage‐level conservation strategies in high Himalaya which primarily relies on snow leopard‐focused ...
Manvi Sharma   +5 more
wiley   +1 more source

Recent advances in data‐driven and artificial intelligence‐integrated perovskite solar cells: From design to self‐driving laboratories

open access: yesInfoMat, EarlyView.
To address the limitations of conventional trial‐and‐error approaches, perovskite solar cell research is shifting toward a new paradigm that utilizes datasets and AI. This review examines the fundamental elements of data‐driven and AI‐integrated research: data platforms, AI methodologies, and self‐driving laboratories, demonstrating how their ...
Jaehee Lee   +5 more
wiley   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

open access: yesInterdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li   +10 more
wiley   +1 more source

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