Results 51 to 60 of about 1,425,533 (307)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The effect of house price changes on cohort consumption in Turkey
Central Bank Review, 2017 This paper analyzes the relationship between house prices and household consumption in Turkey. We utilize twelve consecutive waves of the Turkish Statistical Institute (TURKSTAT) Household Budget Surveys (HBS) from 2003 to 2014.
Evren Ceritoğlu
doaj +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Revista Tiempo & Economía, 2022 Este documento analiza el alcance de los programas sociales focalizados con transferencias condicionadas en la participación política femenina. Para ello hace un estudio de caso del programa Familias en Acción en Colombia entre los años 2007-2014 ...
Lorena Andrea López Barrera
doaj +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Liquidity Constraints and Durable/Non-durable Consumption Relationship in Iran
برنامهریزی و بودجه, 2019 In a rational expectation utility optimization model, the consumption profile is smoothed over time and, under some simplifying assumptions, it equals a constant fraction of total lifetime income.
Zahra Shahidi +2 more
doaj
Measuring Non-Linear Absolute Mobility in Distribution of Income in Iran [PDF]
پژوهشهای اقتصادی, 2016 In most countries, there is no panel data for different households over time. However, cross-sectional data are usually available. Using a cross-sectional dataset, a given group of households cannot be examined for subsequent years. To solve this problem,
Hossein Raghfar +2 more
doaj
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Bilgi ve iletişim teknolojileri kullanımının mikro belirleyicileri: Pseudo panel veri analizi
Afyon Kocatepe Üniversitesi İktisadi ve İdari Bilimler Fakültesi DergisiBu çalışma Türkiye için bilgi ve iletişim teknolojileri (BİT) kullanımını etkileyen olası faktörleri belirlemeyi amaçlamaktadır. Bu amaçla, 2016-2021 dönemine ilişkin altı yıllık bir mikro veri seti kullanılarak BİT yaygınlığı incelenmiştir.
Berat Harman, Zehra Abdioğlu
doaj +1 more source
Infrastructure and Trade: An Empirical Study Based on China and Selected Asian Economies
SAGE Open, 2021 We empirically determine the role of different forms of infrastructure on a country’s trade. We use an augmented gravity model that incorporates infrastructure in the estimation of merchandise trade flows.
Imran Ur Rahman +5 more
doaj +1 more source