Results 41 to 50 of about 78,346 (261)

Gender Earning Difference between Public and Private Sector of Pakistan

Pakistan Journal of Gender Studies, 2023
The study is an attempt to observe the earning differences between male and female of the public and private sector in Pakistan by employing nationally representative Pakistan Labor Force Survey (PLFS) data for the period 2006 - 2021. In order to perform
Dr. Asghar Ali, Dr. Noman Saeed, Mr. Sohail Javed   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

SNPMClust: Bivariate Gaussian Genotype Clustering and Calling for Illumina Microarrays

Journal of Statistical Software, 2016
SNPMClust is an R package for genotype clustering and calling with Illumina microarrays. It was originally developed for studies using the GoldenGate custom genotyping platform but can be used with other Illumina platforms, including Infinium BeadChip ...
Stephen W. Erickson, Joshua C. Callaway
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Inequality in Educational Opportunities Based on Income for Generations in Iran [PDF]

فصلنامه پژوهش‌های اقتصادی ایران, 2013
Education is considered as a significant determinant of earnings inequality; however, there are sensible differences in the educational attainment for individuals.
Hossein Raghfar, MirHossein Mousavi, Batool Azari Beni   +2 more
doaj  

Migration and Asylum Flows to Germany: New Insights Into the Motives

Politics and Governance, 2021
This study analyzes the determinants of both total migration and asylum migration to Germany. For the analysis, a comprehensive empirical model is set up that includes climate change, economic opportunities, such as per capita income differentials, links
Felicitas Nowak-Lehmann, Adriana Cardozo, Inmaculada Martínez-Zarzoso   +2 more
doaj   +1 more source

The Consumption Expenditure of Households in Turkey: Demand System Estimation with Pseudo Panel Data [PDF]

International Conference on Eurasian Economies, 2013
In this study, micro data sets obtained by 2005 and 2009 Household Budget Surveys compiled by Turkish Statistical Institute were used to estimate the parameters of household consumption demand and calculate the income-demand elasticities of consumer goods.
Seda Şengül, Çiler Sigeze
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Pseudo-Panel Decomposition of the Blinder–Oaxaca Gender Wage Gap

Econometrics
This article introduces a novel approach to decomposing the Blinder–Oaxaca gender wage gap using pseudo-panel data. In many developing countries, panel data are not available; however, understanding the evolution of the gender wage gap over time requires
Jhon James Mora, Diana Yaneth Herrera
doaj   +1 more source