Results 51 to 60 of about 209,229 (205)

Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock   +4 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Forty years of metonymy

open access: yesReview of Cognitive Linguistics, 2022
AbstractThis study contributes to the existing body of research that aims at showing the impact of metonymy in grammar. In this case, new evidence will be provided by exploring the English pseudo-partitive construction of time measurement, illustrated byten years of marriage.
openaire   +3 more sources

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

The Terwilliger polynomial of a Q-polynomial distance-regular graph and its application to pseudo-partition graphs

open access: yesLinear Algebra and its Applications, 2015
Let $Γ$ be a $Q$-polynomial distance-regular graph with diameter at least $3$. Terwilliger (1993) implicitly showed that there exists a polynomial, say $T(λ)\in \mathbb{C}[λ]$, of degree $4$ depending only on the intersection numbers of $Γ$ and such that $T(η)\geq 0$ holds for any non-principal eigenvalue $η$ of the local graph $Γ(x)$ for any vertex $x\
Alexander L. Gavrilyuk, Jack H. Koolen
openaire   +3 more sources

On the Types and the Structure of Partitives [PDF]

open access: yes, 2013
In this paper it is claimed that there is a new type of partitive in Japanese which has never been treated as partitives in Japanese. Included in this type of partitive are Alternative Questions (AltQs) and constructions involving disjunction.
Miyama Mioko
core  

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree   +9 more
wiley   +1 more source

Sentenças clivadas e pseudo-clivadas no português brasileiro [PDF]

open access: yes, 2001
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e ExpressãoO presente trabalho tem como objetivo descrever e analisar o comportamento sintático das sentenças clivadas e pseudo-clivadas do português brasileiro a ...
Assis, Cristiane Krug de
core  

Pseudo-read Kraken classifications. [PDF]

open access: yes, 2018
The above plot shows the 20 eukaryotic pathogen genomes with the greatest numbers of pseudo-reads that Kraken identified as matching foreign species when searching against database containing bacteria, viruses, archaea, and a limited set of vertebrate ...
Steven L. Salzberg (70641)   +1 more
core   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

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