Results 171 to 180 of about 200,321 (289)

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

open access: yesAdvanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen   +14 more
wiley   +1 more source

Experiments and physical Investigation on the adsorption of methylene on activated carbon. [PDF]

open access: yesSci Rep
Bouzgarrou SM   +5 more
europepmc   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

open access: yesAdvanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du   +5 more
wiley   +1 more source

Diffusion‐MRI‐Based Estimation of Cortical Architecture via Machine Learning (DECAM) in Primate Brains

open access: yesAdvanced Science, EarlyView.
We present Diffusion‐MRI‐based Estimation of Cortical Architecture via Machine Learning (DECAM), a deep‐learning framework for estimating primate brain cortical architecture optimized with best response constraint and cortical label vectors. Trained using macaque brain high‐resolution multi‐shell dMRI and histology data, DECAM generates high‐fidelity ...
Tianjia Zhu   +7 more
wiley   +1 more source

Impact of functionalization linker chemistry on cellulase immobilization: a comparative study of TEOS, APTS, and MPTS functionalized magnetic nanoparticles. [PDF]

open access: yesRSC Adv
Lamburghini Brandão L   +10 more
europepmc   +1 more source

Atomistic Understanding of 2D Monatomic Phase‐Change Material for Non‐Volatile Optical Applications

open access: yesAdvanced Science, EarlyView.
Antimony is a promising monatomic phase‐change material. Scaling down the film thickness is necessary to prolong the amorphous‐state lifetime, but it alters the optical properties. The combined computational and experimental study shows that, as thickness decreases, the extinction coefficient and optical contrast are reduced in the near‐infrared ...
Hanyi Zhang   +10 more
wiley   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

open access: yesAdvanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang   +8 more
wiley   +1 more source

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