Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li +10 more
wiley +1 more source
A sonochemical strategy integrating enzymatic conversion and purification for efficient production of secondary flavonoid glycosides from Epimedium. [PDF]
Ye L +6 more
europepmc +1 more source
The prevailing neglect of cellular hierarchies in current spatial transcriptomics deconvolution often obscures cellular heterogeneity and impedes the identification of fine‐grained subtypes. To address this issue, HIDF employs a cluster‐tree and dual regularization to systematically model cellular hierarchical structures.
Zhiyi Zou +5 more
wiley +1 more source
Insights into adsorbent-based pharmaceutical wastewater treatment and future developments toward sustainability. [PDF]
Sporsho SS +10 more
europepmc +1 more source
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li +8 more
wiley +1 more source
ANOVA and design expert model for discoloring of azo benzene derivative dye used mesoporous aluminum silicon oxide nanoparticles. [PDF]
Adly YM +5 more
europepmc +1 more source
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong +10 more
wiley +1 more source
Surface-cleaned hydroxyapatite nanowires for aqueous copper ion removal: performance, adsorption mechanisms and membrane filtration application. [PDF]
Jiang Y, Zhang S, Li J, Tan J.
europepmc +1 more source
SiCmiR Atlas: Single‐Cell miRNA Landscape Reveals Hub‐miRNA and Network Signatures in Human Cancers
SiCmiR predicts mature miRNA activity at single‐cell resolution using only 977 landmark genes, enabling scalable reconstruction of miRNA landscapes across diverse tissues and disease contexts. The SiCmiR Atlas integrates 9.36 million cells with analytical tools for hub‐miRNA discovery, biomarker prioritization, and regulatory network interrogation ...
Xiao‐Xuan Cai +12 more
wiley +1 more source
Surface-functionalized cigarette butts as efficient adsorbents for Cr(VI) removal and mechanistic insights. [PDF]
Charoenpanich J +4 more
europepmc +1 more source

