Results 221 to 230 of about 1,005,462 (289)

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Nickel‐Catalyzed Twofold Conjunctive Coupling via Philicity‐Alternating Radical Relay

Advanced Science, EarlyView.
Herein, we disclose a nickel‐catalyzed twofold conjunctive coupling that enables a four‐component assembly involving an activated alkene, a 1,3‐enyne, and both alkyl and aryl halides. Multiple C–C bonds are selectively constructed through a philicity‐alternating radical relay and the selective radical capture by the nickel catalyst.
Ji Hwan Jeon, Da Hye Kim, Gun Ha Kim, Gyuhwan Sim, Jan‐Uwe Rohde, Byunghyuck Jung, Sangwon Seo, Sung You Hong   +7 more
wiley   +1 more source

Purification of Isosorbide via Ion Exchange Resin for High-Performance Bio-Based Polycarbonate. [PDF]

Materials (Basel)
Han F, Zhang Y.
europepmc   +1 more source

EDTA‐Functionalized Nanoscale Metal–Organic Framework for Onco‐Cardiology via Radiochemotherapy Synergy and Spatiotemporally Matched Iron Chelation

Advanced Science, EarlyView.
Doxorubicin (DOX)‐induced cardiotoxicity is a major limitation to its broader clinical application, while cardioprotective interventions often risk reducing the anticancer efficacy of DOX. To address these challenges, this work constructs an EDTA‐functionalized metal–organic framework that enhances tumor therapy and provides efficient cardioprotection ...
Daojing Yuan, Liyang Tian, Luwen Zhuang, Yongyu Liang, Lingfei Chen, Xuetao Wang, Yanli Li, Xiyong Yu, Teng Gong   +8 more
wiley   +1 more source

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

Advanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo, Ying Yang, Zizhen Fu, Fengqi Liu, Susu Fang, Kele Xu, Shanshan Wang   +6 more
wiley   +1 more source

Optimization and adsorption mechanisms of vanadium removal by Fe-Pillared bentonite as an efficient adsorbent. [PDF]

Sci Rep
Etaati A, Soleimani M.
europepmc   +1 more source

Biosorption of Cu²⁺ and Zn²⁺ by Rhodotorula sp. Kt, a Yeast Isolated from Acid Mine Drainage. [PDF]

Materials (Basel)
Barseghyan S, Vardanyan N, Abrahamyan N, Melkonyan Z, Castro L, Muñoz JA, Vardanyan A.   +6 more
europepmc   +1 more source

Engineering of a kaolin/SLS-functionalized biochar@β-cyclodextrin composite for adsorption of <i>o</i>-nitrophenol; optimization, mechanistic study, and Box-Behnken design. [PDF]

RSC Adv
Eltaweil AS, Al Harby N, El Batouti M, Abd El-Monaem EM.   +3 more
europepmc   +1 more source

Boosting adsorption capacity of methylene blue dye by multiple functional ZnO-g-C₃N₄/ carboxymethyl chitosan/alginate -grafted polyacrylic acid composite. [PDF]

Sci Rep
Khalaf-Allah ASA, Sultan M, Abdel-Monem YK, El-Gamasy SM, El-Sayed WA, Youssef AM.   +5 more
europepmc   +1 more source

Unveiling the mechanism of ultrasound-assisted phenolic extraction from Psidium cattleianum leaves: Kinetic, mass transfer, and thermodynamic insights. [PDF]

Ultrason Sonochem
Huynh HD, Nargotra P, Wang HD, Tsai YH, Chiu CC, Shieh CJ, Liu YC, Kuo CH.   +7 more
europepmc   +1 more source