Results 231 to 240 of about 1,464,780 (333)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

The mandala of Legendrian dualities for pseudo-spheres in Lorentz-Minkowski space and "flat" spacelike surfaces

open access: yesThe mandala of Legendrian dualities for pseudo-spheres in Lorentz-Minkowski space and "flat" spacelike surfaces
Using the Legnedrian duarities between surfaces in pseudo-spheres in Lorentz-{Minkow}{ski} 4-space, we study various kind of flat surfaces in pseudo-spheres. We consider a surface in the pseudo-sphere and its dual surface. Flatness of a surface is defined by the degeneracy of the dual surface similar to the case for the Gauss map of a flat surface in ...
openaire  

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

open access: yesAdvanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu   +14 more
wiley   +1 more source

TrIPP: a trajectory iterative pKa predictor. [PDF]

open access: yesBioinformatics
Matsingos C, Man KF, Fornili A.
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

DNATCO v5.0: integrated web platform for 3D nucleic acid structure analysis. [PDF]

open access: yesNucleic Acids Res
Černý J   +6 more
europepmc   +1 more source

High‐Throughput Data Generation and Transfer Learning Enabled Microstructure‐Property Integrated Design of Nickel‐Based Powder Metallurgy Superalloy

open access: yesAdvanced Science, EarlyView.
An integrated transfer learning framework integrates CALPHAD simulations, diffusion‐multiple experiments, and literature data to predict long‐term microstructural stability and short‐term mechanical properties of Ni‐based powder metallurgy superalloys. Based on these model predictions, a high‐performance, low‐density alloy, USTB‐PM750, is designed from
Zixin Li   +8 more
wiley   +1 more source

Personalized MR-Informed Diffusion Models for 3D PET Image Reconstruction. [PDF]

open access: yesIEEE Trans Radiat Plasma Med Sci
Webber G, Hammers A, King AP, Reader AJ.
europepmc   +1 more source

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