Results 141 to 150 of about 2,748,326 (232)

Single‐Cell Reporter Dynamics During the First Two Rounds of Rhinovirus Plaque Growth

open access: yesCytometry Part A, EarlyView.
ABSTRACT When infection spreads from an initially infected cell through a cell monolayer, the resulting plaque records successive rounds of virus–cell interaction. Fluorescent reporter viruses permit this process to be followed at single‐cell resolution, but whether secondary infected cells retain detectable signatures associated with their plaque of ...
Rahul Ramachandran   +2 more
wiley   +1 more source

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

open access: yesDrug Testing and Analysis, EarlyView.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda   +9 more
wiley   +1 more source

Mechanism and disaster control new technology of strong ground pressure manifestation in ultra‐large mining face

open access: yesDeep Underground Science and Engineering, EarlyView.
In response to the problem of strong mining pressure manifestation along the goaf roadway in a thick coal seam mining area, this study uses a new type of combined blasting roof cutting technology to effectively control the manifestation and deformation of mining pressure along the goaf roadway.
Xiaoding Xu   +6 more
wiley   +1 more source

Modeling proppant transport and settling in a 3D propagating fracture

open access: yesDeep Underground Science and Engineering, EarlyView.
A versatile multiphysics tool is presented for simulating the complex processes involved in hydraulic fracturing treatments. The model couples fracture opening and propagation, variable‐density slurry flow, and proppant particle transport within the multiphysics object‐oriented simulation environment framework, based on two‐phase mixture equations and ...
Robert Egert   +2 more
wiley   +1 more source

Different from bone: Tooth formation and enameloid mineralization are not affected by reduced dietary phosphorus intake

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Vertebrates rely on phosphorus intake for skeletal mineralization. In humans, hypomineralized teeth associated with rickets, hypophosphatemia, hypophosphatasia, or idiopathic molar‐incisor‐hypomineralization pose significant problems.
S. Cotti   +8 more
wiley   +1 more source

Hemodynamic loading regulates formation and patterning of atrial pectinate muscles in the chick embryo

open access: yesDevelopmental Dynamics, EarlyView.
Development and differentiation of the atrial myocardium. Hemodynamic loading triggers shear stress response, which is essential for pectinate muscle formation; mechanical stretching is important for the expression of chamber myocardium markers and proper maturation of the atrial contractile and conductive properties.
C. Neradilova   +7 more
wiley   +1 more source

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