Results 301 to 310 of about 1,059,621 (384)

Microbiome‐Informed Dosing: Exploring Gut Microbial Communities Impact on Mycophenolate Enterohepatic Circulation and Therapeutic Target Achievement

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pharmacomicrobiomics is an emerging field due to important microbiome effects on pharmacokinetics and clinical outcomes. However, the application of this knowledge remains limited. Mycophenolic acid (MPA) is the primary active metabolite of the immunosuppressant, mycophenolate mofetil (MMF).
Abdelrahman Saqr   +4 more
wiley   +1 more source

The Impact of Redox Mediators on the Electrogenic and Physiological Properties of Synechocystis sp. PCC 6803 in a Biophotovoltaic System

open access: yesChemSusChem, EarlyView.
Redox mediators are essential to promote the electrogenic activity of cyanobacteria in biophotovoltaics. In this work, we systematically evaluates three representative mediators about their influence on the cyanobacterial growth, photosynthetic efficiency, and electrogenic activity. The results reveal distinct impacts of different mediators, despite of
Jianqi Yuan   +6 more
wiley   +1 more source

Shaping the future of tobacco through microbial insights: a review of advances and applications. [PDF]

open access: yesFront Bioeng Biotechnol
Hu W   +7 more
europepmc   +1 more source

Combining photocatalytic oxidation of β‐chlorohydrins with carbonyl bioreduction in a deracemization approach

open access: yesChemSusChem, Accepted Article.
Enantiopure β‐chlorohydrins are valuable intermediates in organic synthesis, acting as chiral building blocks for obtaining biologically active compounds. This work presents a one‐pot two‐step linear sequence for the efficient deracemization of β‐chlorohydrins by combining a photocatalytic alcohol oxidation with a stereoselective carbonyl bioreduction ...
Sara Filgueira   +3 more
wiley   +1 more source

Synthesis of 19‐Hydroxyarachidonic Acid by Fungal Peroxygenases: An Experimental and Computational Study

open access: yesChemSusChem, Accepted Article.
Hydroxylated derivatives of arachidonic acid play crucial roles in physiology and inflammation response, with distinct biological effects for (R)‐ and (S)‐enantiomers, highlighting their pharmaceutical relevance. Here, we harness recombinant unspecific peroxygenases (UPOs)—from the fungi Coprinopsis cinerea (rCciUPO) and Agrocybe aegerita (rAaeUPO ...
Alejandro González-Benjumea   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy