Results 251 to 260 of about 3,746,898 (399)

Resistance patterns and virulence factors of Pseudomonas aeruginosa in hospitalized patients: A Saudi Arabian study. [PDF]

open access: yesSci Rep
Moursi SA   +10 more
europepmc   +1 more source

Artificial Intelligence Revolutionizes Anti‐Infective Drug Discovery: From Target Identification to Lead Optimization

open access: yesiMetaMed, EarlyView.
Artificial intelligence (AI) technology is revolutionizing antimicrobial drug development. In response to increasingly severe antimicrobial resistance challenges, AI can efficiently predict pathogen evolutionary trends, identify potential drug targets, and accelerate compound design and optimization, thereby significantly shortening the development ...
Kexin Li   +6 more
wiley   +1 more source

Microbial Primer: The R-pyocins of <i>Pseudomonas aeruginosa</i>. [PDF]

open access: yesMicrobiology (Reading)
Estrada I   +4 more
europepmc   +1 more source

Death after transplantation. An analysis of sixty cases [PDF]

open access: yes, 1967
Dahrling, BE   +3 more
core   +1 more source

Soil‐borne legacy facilitates the dissemination of antibiotic resistance genes in soil–plant continua

open access: yesiMeta, EarlyView.
Antimicrobial resistance (AMR) disseminates throughout the soil–plant continuum via complex microbial interactions. Plants shape root‐ and leaf‐associated microbiomes that sustain plant health; however, soil‐borne legacies—enriched with antibiotic‐producing microbes and resistance genes—govern AMR dynamics across agroecosystems.
Zufei Xiao   +11 more
wiley   +1 more source

Salvage Therapy with Ceftolozane-Tazobactam for Multidrug-Resistant Pseudomonas aeruginosa Infections

open access: yesAntimicrobial Agents and Chemotherapy, 2016
J. Castón   +5 more
semanticscholar   +1 more source

TargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus

open access: yesInterdisciplinary Medicine, EarlyView.
TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan   +2 more
wiley   +1 more source

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