Results 311 to 320 of about 3,613,662 (378)

Efficient Synthesis of Steroidal Intermediates with a C17 Side Chain from Phytosterols by Genetically Modified Mycolicibacterium neoaurum NRRL B‐3805 Strain

ChemistryOpen, EarlyView.
Two genetically modified strains are designed and constructed to produce 22‐hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) and 3‐oxo‐4,17‐pregnadiene‐20‐carboxylic acid methyl ester (PDCE) by disrupting and overexpressing the aldolase gene (thl) in the genetically modified strains of Mycolicibacterium neoaurum NRRL B‐3805, respectively, which are useful ...
Xuemei Li, Liangyan Zhu, Qiong Wu, Rui Zhang, Yiyin Liu, Na Liu, Jinhui Feng, Qiaqing Wu, Dunming Zhu   +8 more
wiley   +1 more source

Assessing the Levels and Types of Bacterial Contamination in Cosmetic Brushes: Implications for Beauty and Hygiene in Jeddah City. [PDF]

Int J Microbiol
Attar RMS, Imam MA.
europepmc   +1 more source

Crystal Structure–Activity Relationship of Some MeO Phenylacrylonitriles: Dual Antimicrobial–Cytotoxic Effects and in Silico Perspectives

ChemistryOpen, EarlyView.
Methoxy‐phenylacrylonitriles (2a–c) are synthesized and characterized by fourier‐transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, and X‐ray crystallography (for 2a,b). Compound 2b shows selective cytotoxicity against MCF‐7 cells (IC50: 34 μM) and enhances activity against Gram‐positive bacteria. Molecular docking reveals strong
Leyla Babali Özen, Öner Ekici, Furkan Özen, Süleyman Berberler, Gül Özkan, Betül Yılmaz Öztürk, Pınar Oztopcu‐Vatan, Cansu Filik İşçen, Günseli Turgut Cin   +8 more
wiley   +1 more source

The Role of <i>bla</i>OXA-101 and <i>bla</i>OXA-573 in Extensively Drug-Resistant/ Pan Drug-Resistant (XDR/PDR) <i>Pseudomonas aeruginosa</i> Resistance to Ceftazidime-Avibactam. [PDF]

Infect Drug Resist
Kang Y, Cui J.
europepmc   +1 more source

Infectious Morbidity During Pediatric Acute Myeloid Leukemia Chemotherapy in a High‐Income Country: A 15‐Year Population‐Based Overview

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Infection causes significant morbidity and mortality in pediatric acute myeloid leukemia (pAML). This study describes the incidence and risk factors of bloodstream infection (BSI) and invasive fungal infection (IFI) in pAML. Methods A retrospective chart review was performed of patients treated according to the ANLL‐97/AML‐12 (N =
Emily R. Schwartz, Kim Klein, Birgit I. Lissenberg‐Witte, Tom F. W. Wolfs, Valérie de Haas, Bianca Goemans, Natasja Dors, Marry M. van den Heuvel‐Eibrink, Rutger R. G. Knops, Wim J. E. Tissing, Birgitta A. Versluys, C. Michel Zwaan, Raphaële R. L. van Litsenburg, Gertjan J. L. Kaspers   +13 more
wiley   +1 more source

Ceftazidime-avibactam plus aztreonam cocktail for the treatment of VIM-producing Pseudomonas aeruginosa infections: good enough to have another? [PDF]

J Antimicrob Chemother
Pina-Sánchez M, Rua M, López-Causapé C, Bilbao I, Sastre-Femenia MÀ, Oliver A, Del Pozo JL.   +6 more
europepmc   +1 more source

Harnessing Molecular and Bioactivity Network Analysis to Prioritize Antibacterial Compound Isolation From Ant‐Associated Fungi

Phytochemical Analysis, EarlyView.
ABSTRACT Introduction Antimicrobial resistance is a global public health problem that requires the development of new bioactive compounds. In this context, metabolomic analyses can expedite the research of fungal metabolites as a valuable resource. Objectives To investigate the metabolic profiles and isolate antibacterial compounds from micromycetes ...
Ángel S. Aguilar‐Colorado, Jesús Morales‐Jiménez, José Rivera‐Chávez   +2 more
wiley   +1 more source

Developing Gingerol-Based Analogs against Pseudomonas aeruginosa Infections

ACS Omega
Taehyeong Lim, Soyoung Ham, Han-Shin Kim, Ji-Eun Yang, Hyunwoong Lim, Hee-Deung Park, Youngjoo Byun   +6 more
doaj   +1 more source