Results 271 to 280 of about 355,849 (306)

Structure-filtered search of enzyme variants. [PDF]

Comput Struct Biotechnol J
Porri L, Castillo S, Jouhten P.
europepmc   +1 more source

Dual‐Emission Carbon Dot Nanozymes Mitigate Salt Stress and Enhance Photosynthesis for Crop Germination and Growth

Advanced Science, EarlyView.
Dual‐emission carbon dot nanozymes are synthesized via microwave method. The nanozymes enhance photosynthesis corn seedlings through spectral‐matched light conversion. Their superoxide dismutase‐mimetic activity scavenges salt stress‐induced reactive oxygen species and circumvents energy‐intensive stress responses.
Chengfu Su, Xin Peng, Jingying Tan, Yujie Chang, Naifei Pan, Haiying Chen, Xiaokai Xu, Lei Han   +7 more
wiley   +1 more source

Opening wedge high tibial osteotomy using patient-specific instruments and custom-made plates results in accurate correction and improved clinical outcome measures at 1-year follow-up. [PDF]

J Exp Orthop
Jud L, Biner M, Vlachopoulos L, Sigrist B, Fucentese SF.   +4 more
europepmc   +1 more source

METTL10‐Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression

Advanced Science, EarlyView.
METTL10‐mediated methylation of PIAS3 at K442 inhibits its SUMO E3 ligase activity toward MITF. This reduces MITF SUMOylation and subsequent RNF4‐mediated ubiquitination, leading to MITF protein accumulation and gastric cancer progression. Abstract Metabolic dysregulation plays a significant role in the development of gastric cancer (GC).
Jinshui Tan, Huiwen Zhou, Jingsong Ma, Chensong Zhang, Yuhua Tan, Baoding Zhang, Jiabao Zhao, Ao Cheng, Chengyu Yang, Meijuan Xu, Shengyi Zhou, Yubo Xiong, Zeyang Lin, Guangchao Pan, Wenjie Ye, Mengya Zhong, Yang Yang, Yifan Zhuang, Shao‐Wei Li, Xianming Deng, Xuehui Hong   +20 more
wiley   +1 more source

OSH45, a homeobox transcription factor, coordinates low-phosphate adaptation in rice. [PDF]

Front Plant Sci
Lu H, Jin K, Luo Y, Wu Y, Liu Y, Xu J, Mao C.   +6 more
europepmc   +1 more source

Phase‐Space Generalized Brillouin Zone For Spatially Inhomogeneous Non‐Hermitian Systems

Advanced Science, EarlyView.
A novel phase‐space generalized Brillouin zone (GBZ) framework to devised captures the interplay of spatial inhomogeneity and non‐local non‐Hermitian effects. This reveals new degrees of freedom such as jumps in the bifurcated GBZ, as well as new routes for topological protection, with potential applications in characterizing inhomogeneous or ...
Qingya Li, Hui Jiang, Ching Hua Lee
wiley   +1 more source

Mediators implementation and delivery: the falls management exercise programme (FaME). [PDF]

BMC Health Serv Res
Manning F, Ventre JP, Brough G, Hawley-Hague H, Hulme C, Kendrick D, Logan P, Mahmoud A, Masud T, Orton E, Skelton DA, Timmons S, Todd C, Goodwin VA.   +13 more
europepmc   +1 more source

Interpretable PROTAC Degradation Prediction With Structure‐Informed Deep Ternary Attention Framework

Advanced Science, EarlyView.
PROTAC‐STAN, a structure‐informed deep learning framework is presented for interpretable PROTAC degradation prediction. By modeling molecular hierarchies and protein structures, and simulating ternary interactions via a novel attention network, PROTAC‐STAN achieves significant performance gains over baselines.
Zhenglu Chen, Chunbin Gu, Shuoyan Tan, Xiaorui Wang, Yuquan Li, Mutian He, Ruiqiang Lu, Shijia Sun, Chang‐Yu Hsieh, Xiaojun Yao, Huanxiang Liu, Pheng‐Ann Heng   +11 more
wiley   +1 more source

Comparing Constant and Transient Membrane Transport Parameters for Use in Wave Desalination Models. [PDF]

Membranes (Basel)
Sitterley KA, Binger Z, Jenne DS.
europepmc   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source