Results 11 to 20 of about 2,751 (156)

Individual Differences in Boldness Influence Working Memory and Stress-Induced Repetitive Behaviors in Zebrafish. [PDF]

Eur J Neurosci
This study investigates the influence of boldness on zebrafish cognition and repetitive behaviors, focusing on the role of stress. Boldness was measured using the novel tank diving test and quantified with a boldness index. Zebrafish were exposed to a naturalistic stressor, conspecific alarm substance (CAS), before behavioral assessment in the free ...
Fontana BD, Moraes HS, Pretzel CW, Mohammed KA, Canzian J, Bonan CD, Parker MO, Rosemberg DB.   +7 more
europepmc   +2 more sources

Solanum paranense Extracts and Solanine Present Anti-Inflammatory Activity in an Acute Skin Inflammation Model in Mice. [PDF]

Evid Based Complement Alternat Med, 2017
The aim of the study was to evaluate the anti‐inflammatory activity of the S. paranense crude extract, S. paranense alkaloid fraction, and solanine alkaloid. These samples reduce the croton oil‐induced ear edema in a dose‐dependent manner and a maximum inhibition of 81%, 98%, and 80% in the doses of 1.0, 0.73, and 0.37 mg/ear, respectively.
Piana M, Camponogara C, Boligon AA, Oliveira SM.   +3 more
europepmc   +2 more sources

Uliginosin B, a Possible New Analgesic Drug, Acts by Modulating the Adenosinergic System. [PDF]

Evid Based Complement Alternat Med, 2016
Uliginosin B (ULI) is a natural acylphloroglucinol that has been proposed as a new molecular scaffold for developing analgesic and antidepressant drugs. Its effects seem to be due to its ability to increase monoamines in the synaptic cleft by inhibiting their neuronal uptake without binding to their respective transporters, but its exact mode of action
Stolz ED, da Costa PF, Medeiros LF, Souza A, Battastini AM, von Poser GL, Bonan C, Torres IL, Rates SM.   +8 more
europepmc   +2 more sources

Monoterpenoid terpinen-4-ol exhibits anticonvulsant activity in behavioural and electrophysiological studies. [PDF]

Oxid Med Cell Longev, 2014
Terpinen‐4‐ol (4TRP) is a monoterpenoid alcoholic component of essential oils obtained from several aromatic plants. We investigated the psychopharmacological and electrophysiological activities of 4TRP in male Swiss mice and Wistar rats. 4TRP was administered intraperitoneally (i.p.) at doses of 25 to 200 mg/kg and intracerebroventricularly (i.c.v ...
Nóbrega FF, Salvadori MG, Masson CJ, Mello CF, Nascimento TS, Leal-Cardoso JH, de Sousa DP, Almeida RN, Almeida RN.   +8 more
europepmc   +2 more sources

Can High Altitude Influence Cytokines and Sleep?

Mediators of Inflammation, Volume 2013, Issue 1, 2013., 2013
The number of persons who relocate to regions of high altitude for work, pleasure, sport, or residence increases every year. It is known that the reduced supply of oxygen (O2) induced by acute or chronic increases in altitude stimulates the body to adapt to new metabolic challenges imposed by hypoxia.
Valdir de Aquino Lemos, Ronaldo Vagner Thomatieli dos Santos, Fabio Santos Lira, Bruno Rodrigues, Sergio Tufik, Marco Tulio de Mello, Gustavo Duarte Pimentel   +6 more
wiley   +1 more source

Intraperitoneal Exposure to Nano/Microparticles of Fullerene (C60) Increases Acetylcholinesterase Activity and Lipid Peroxidation in Adult Zebrafish (Danio rerio) Brain

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
Even though technologies involving nano/microparticles have great potential, it is crucial to determine possible toxicity of these technological products before extensive use. Fullerenes C60 are nanomaterials with unique physicochemical and biological properties that are important for the development of many technological applications.
Gonzalo Ogliari Dal Forno, Luiza Wilges Kist, Mariana Barbieri de Azevedo, Rachel Seemann Fritsch, Talita Carneiro Brandão Pereira, Roberta Socoowski Britto, Sílvia Stanisçuaski Guterres, Irene Clemes Külkamp-Guerreiro, Carla Denise Bonan, José María Monserrat, Maurício Reis Bogo, Qaisar Mahmood   +11 more
wiley   +1 more source

Acute Exposure to Microcystin‐Producing Cyanobacterium Microcystis aeruginosa Alters Adult Zebrafish (Danio rerio) Swimming Performance Parameters

Journal of Toxicology, Volume 2011, Issue 1, 2011., 2011
Microcystins (MCs) are toxins produced by cyanobacteria (blue‐green algae), primarily Microcystis aeruginosa, forming water blooms worldwide. When an organism is exposed to environmental perturbations, alterations in normal behavioral patterns occur.
Luiza Wilges Kist, Angelo Luis Piato, João Gabriel Santos da Rosa, Gessi Koakoski, Leonardo José Gil Barcellos, João Sarkis Yunes, Carla Denise Bonan, Maurício Reis Bogo, J. J. Stegeman   +8 more
wiley   +1 more source

Modulation of Sleep Homeostasis by Corticotropin Releasing Hormone in REM Sleep‐Deprived Rats

International Journal of Endocrinology, Volume 2010, Issue 1, 2010., 2010
Studies have shown that sleep recovery following different protocols of forced waking varies according to the level of stress inherent to each method. Sleep deprivation activates the hypothalamic‐pituitary‐adrenal axis and increased corticotropin‐releasing hormone (CRH) impairs sleep.
Ricardo Borges Machado, Sergio Tufik, Deborah Suchecki, Jessica A. Mong   +3 more
wiley   +1 more source

Avanços em psicofarmacologia - mecanismos de ação de psicofármacos hoje [PDF]

Brazilian Journal of Psychiatry, 1999
Desde o início da história da psicofarmacologia moderna, na década de 40, vários avanços foram obtidos na elucidação do mecanismo de ação dos compostos psicoativos.
Clarice Gorenstein, Cristóforo Scavone
doaj   +1 more source

Psicofarmacología terapéutica y cosmética. Riesgos y límites [PDF]

, 2009
In this paper, I analyze risks and limits of the current psychopharmacology and how both are promoting a new social interpretation of health concept.
Echarte-Alonso, L.E. (Luis Enrique)
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