Irismar - Psicofarmacologia Clínica [PDF]
Silvio Luiz Morais
doaj +6 more sources
Psicofarmacologia de antidepressivos [PDF]
O advento de medicamentos antidepressivos tornou a depressão um problema médico, passível de tratamento. Nas últimas cinco décadas, a psicofarmacologia da depressão evoluiu muito e rapidamente.
Ricardo Alberto Moreno +2 more
doaj +4 more sources
What do we know about the sleep effects of caffeine used to treat apnoea of prematurity? A systematic review of the literature [PDF]
Objective Scientific scrutiny has proved the safety and benefits of caffeine to treat apnoea of prematurity (AOP). However, there is no consensus on the effects of this treatment on sleep, especially considering the key role of adenosine and early brain ...
Ana Renata Pinto de Toledo +5 more
doaj +2 more sources
Standardizing Zebrafish Behavioral Paradigms Across Life Stages: An Effort Towards Translational Pharmacology [PDF]
Zebrafish is a prominent vertebrate model, with many of its advantages related to its development, life cycle, and translational ability. While a great number of behavioral phenotypes and tasks to evaluate them are available, longitudinal studies across ...
Barbara Dutra Petersen +6 more
doaj +2 more sources
Solanum paranense Extracts and Solanine Present Anti-Inflammatory Activity in an Acute Skin Inflammation Model in Mice. [PDF]
The aim of the study was to evaluate the anti‐inflammatory activity of the S. paranense crude extract, S. paranense alkaloid fraction, and solanine alkaloid. These samples reduce the croton oil‐induced ear edema in a dose‐dependent manner and a maximum inhibition of 81%, 98%, and 80% in the doses of 1.0, 0.73, and 0.37 mg/ear, respectively.
Piana M +3 more
europepmc +2 more sources
A psicofarmacologia geriátrica
O desenvolvimento da psicofarmacologia geriátrica ocorreu nos últimos 30 anos após as grandes modificações ocorridas na psiquiatria e no acelerado envelhecimento da população.
Érico Castro-Costa, Sergio Luís Blay
doaj +2 more sources
Uliginosin B, a Possible New Analgesic Drug, Acts by Modulating the Adenosinergic System. [PDF]
Uliginosin B (ULI) is a natural acylphloroglucinol that has been proposed as a new molecular scaffold for developing analgesic and antidepressant drugs. Its effects seem to be due to its ability to increase monoamines in the synaptic cleft by inhibiting their neuronal uptake without binding to their respective transporters, but its exact mode of action
Stolz ED +8 more
europepmc +2 more sources
Psicofarmacologia e análise existencial [PDF]
A psicofarmacologia e a análise existencial utilizam métodos de investigação científica e psiquiátrica diferentes, visando melhorar a prática psiquiátrica.
Roland Kuhn
doaj +3 more sources
Monoterpenoid terpinen-4-ol exhibits anticonvulsant activity in behavioural and electrophysiological studies. [PDF]
Terpinen‐4‐ol (4TRP) is a monoterpenoid alcoholic component of essential oils obtained from several aromatic plants. We investigated the psychopharmacological and electrophysiological activities of 4TRP in male Swiss mice and Wistar rats. 4TRP was administered intraperitoneally (i.p.) at doses of 25 to 200 mg/kg and intracerebroventricularly (i.c.v ...
Nóbrega FF +7 more
europepmc +2 more sources
Purinergic Signaling in the Pathophysiology and Treatment of Huntington’s Disease [PDF]
Huntington’s disease (HD) is a devastating, progressive, and fatal neurodegenerative disorder inherited in an autosomal dominant manner. This condition is characterized by motor dysfunction (chorea in the early stage, followed by bradykinesia, dystonia ...
Melissa Talita Wiprich +4 more
doaj +2 more sources

