Editorial: Zebrafish as a model for pharmacological and toxicological research [PDF]
Carla Denise Bonan, Anna Maria Siebel
doaj +2 more sources
Solanum paranense Extracts and Solanine Present Anti-Inflammatory Activity in an Acute Skin Inflammation Model in Mice. [PDF]
The aim of the study was to evaluate the anti‐inflammatory activity of the S. paranense crude extract, S. paranense alkaloid fraction, and solanine alkaloid. These samples reduce the croton oil‐induced ear edema in a dose‐dependent manner and a maximum inhibition of 81%, 98%, and 80% in the doses of 1.0, 0.73, and 0.37 mg/ear, respectively.
Piana M +3 more
europepmc +2 more sources
O ensino da psicofarmacologia na formação inicial dos psicólogos portugueses
A psicofarmacologia representa, cada vez mais, uma área de conhecimento com importantes implicações na atuação profissional dos psicólogos. Em vários países, tem-se assistido, ao longo dos últimos anos, a uma crescente importância dada à formação em ...
Ana Beatriz Leite +3 more
doaj +1 more source
Uliginosin B, a Possible New Analgesic Drug, Acts by Modulating the Adenosinergic System. [PDF]
Uliginosin B (ULI) is a natural acylphloroglucinol that has been proposed as a new molecular scaffold for developing analgesic and antidepressant drugs. Its effects seem to be due to its ability to increase monoamines in the synaptic cleft by inhibiting their neuronal uptake without binding to their respective transporters, but its exact mode of action
Stolz ED +8 more
europepmc +2 more sources
Monoterpenoid terpinen-4-ol exhibits anticonvulsant activity in behavioural and electrophysiological studies. [PDF]
Terpinen‐4‐ol (4TRP) is a monoterpenoid alcoholic component of essential oils obtained from several aromatic plants. We investigated the psychopharmacological and electrophysiological activities of 4TRP in male Swiss mice and Wistar rats. 4TRP was administered intraperitoneally (i.p.) at doses of 25 to 200 mg/kg and intracerebroventricularly (i.c.v ...
Nóbrega FF +7 more
europepmc +2 more sources
O uso de psicodélicos como acesso à consciência primária e sua relação com a teoria dos arquétipos
O objetivo deste artigo foi o de estabelecer relações entre a teoria dos arquétipos de Jung e os resultados de pesquisas com o uso de substâncias psicodélicas, uma das formas de se retornar a um estado de consciência ancestral, também chamada de ...
Guilherme Silva Gonçalves
doaj +1 more source
The experience of Universidade São Francisco with the medical internship in psychiatry using the problem-based learning method [PDF]
In the last few years, medical education has been going through curricular and pedagogical changes with the purpose of educating a new health professional.
Paulin, Luiz Fernando Ribeiro Da Silva +1 more
core +3 more sources
Monosialoganglioside (GM1) is a glycosphingolipid that protects against some neurological conditions, such as seizures and ischemia. Glutaric acidemia type I (GA-I) is an inherited disease characterized by striatal degeneration, seizures, and ...
Michele Rechia Fighera +8 more
doaj +1 more source
Este artigo tem como propósito refletir sobre as dificuldades enfrentadas pelos alunos na aprendizagem e os fatores relacionados ao uso demasiado de medicamentos, principalmente em idade escolar.
Daniela Copetti Santos
doaj +1 more source
The role of the transcription factor NF-kappaB in the molecular mechanisms of action of psychoactive drugs [PDF]
During the last years many efforts have been made in order to elucidate the mechanisms involved in the gene transcription regulation. Special attention has been given to some molecules involved in these regulatory processes, as the transcription factors.
Avellar, Maria Christina Werneck +4 more
core +3 more sources

