Value in the ‘valley of the shadow of death’—When the user is no longer the value arbiter
Abstract The Public Service Logic (PSL) user‐centric perspective on value creation has been one of its main critiques. Scholars argue that for some real‐world applications, such as emergency services, where users cannot engage with service offerings, the PSL must consider the roles of other service actors beyond just facilitators.
Higor Leite, Stephen Osborne
wiley +1 more source
Protective Effect of Thai <i>Perilla frutescens</i> Seed Oil Against Chronic Obstructive Pulmonary Disease Induced by Cigarette Smoke Extract in a Mouse Model. [PDF]
Liamvilairat G +5 more
europepmc +1 more source
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
A Systemic Immune State Axis Distinguishes Psoriatic Arthritis from Psoriasis. [PDF]
Lee YK, Seong HA.
europepmc +1 more source
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton +19 more
wiley +1 more source
Integrating bulk RNA-seq, Mendelian randomization and single-cell RNA-seq to elucidate the roles of lactate metabolism related markers-SLC25A4 and keratinocyte in the pathogenesis of psoriasis. [PDF]
Wang Y, Wang X.
europepmc +1 more source
Effect of Medication Intake on Dental Implant‐Related Outcomes—A Scoping Review
ABSTRACT Objective The objective of this scoping review was to evaluate the effect of systemic medications on dental implant outcomes in medically compromised patients. Material and Methods Electronic and manual searches were conducted for this scoping review.
Alberto Monje +4 more
wiley +1 more source
Forward Planning: A Staffing Framework and Ratios for Psychosocial Oncology and Supportive Care Hiring Practices as Cancer Care Models Evolve. [PDF]
Mayer C +3 more
europepmc +1 more source
PSO-OCSVM based industrial control system communication behavior anomaly detection method
本发明基于OCSVM算法提出了一种基于PSO-OCSVM的工业控制系统通信行为异常检测方法。该发明利用改进的单类支持向量机算法,根据正常的Modbus功能码序列建立正常通信行为轮廓,设计了一种基于粒子群算法(PSO)进行参数优化的PSO-OCSVM方法,建立入侵检测模型,识别出异常的Modbus?TCP通信流量。该发明提高了异常检测的效率及其可靠性 ...
于海斌 +4 more
core
Impact of adalimumab treatment on impairment of non‐professional activities in psoriasis patients
Summary Background and objectives Psoriasis can result in reduced quality of life, work productivity loss, and a significant restriction in non‐professional activities. This study investigates the effects of long‐term treatment with adalimumab regarding work ability, non‐professional activities, and health‐related quality of life in a large real‐word ...
Georgios Kokolakis +4 more
wiley +1 more source

