Results 71 to 80 of about 35,947 (209)

Secukinumab versus adalimumab for psoriatic arthritis: comparative effectiveness up to 48 weeks using a matching-adjusted indirect comparison [PDF]

open access: yes, 2018
Secukinumab and adalimumab are approved for adults with active psoriatic arthritis (PsA). In the absence of direct randomized controlled trial (RCT) data, matching-adjusted indirect comparison can estimate the comparative effectiveness in anti-tumor ...
Gandhi, Kunal   +8 more
core   +2 more sources

IL-17A in the Psoriatic Patients’ Serum and Plaque Scales as Potential Marker of the Diseases Severity and Obesity

open access: yesMediators of Inflammation, 2020
The aim of the study was to evaluate concentrations of IL-17 in the serum and plaque scales of psoriatic patients. We analyzed their association with the clinical activity of the disease and with body mass index (BMI).
Anna Michalak-Stoma   +5 more
doaj   +1 more source

Definition of treatment goals for moderate to severe psoriasis: a European consensus [PDF]

open access: yes, 2010
Patients with moderate to severe psoriasis are undertreated. To solve this persistent problem, the consensus programme was performed to define goals for treatment of plaque psoriasis with systemic therapy and to improve patient care.
A. Nast   +25 more
core   +7 more sources

PACE study: real-life Psoriasis Area and Severity Index (PASI) 100 response with biological agents in moderate-severe psoriasis

open access: yesJournal of Dermatological Treatment, 2017
Few studies have compared the use of different biologics in a real-life setting in plaque psoriasis patients.To compare the efficacy of biologics in psoriasis/psoriatic arthritis patients.Patients treated with adalimumab, etanercept and ustekinumab for at least 16 weeks were included.
Carlo Giovanni, Carrera   +8 more
openaire   +2 more sources

Psoriatic Foot Involvement is the Most Significant Contributor to the Inconsistency Between PASI and DLQI: A Retrospective Study from China

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Jing Yang,1,2 Kun Hu,1,2 Xingyu Li,1,2 Jingjin Hu,1,2 Minjia Tan,1,2 Mi Zhang,1,2 Junchen Chen,1,2 Yehong Kuang1,2 1Department of Dermatology, Xiangya Hospital, Central South University, Changsa, Hunan, People’s Republic of China; 2National Clinical ...
Yang J   +7 more
doaj  

Coffee consumption, metabolic syndrome and clinical severity of psoriasis: Good or bad stuff? [PDF]

open access: yes, 2018
Despite the wide consumption of coffee, its anti-inflammatory effect on clinical severity of psoriasis is still debatable. The aim of this study was to evaluate the association between the coffee consumption and clinical severity of psoriasis in a sample
Annunziata, Giuseppe   +8 more
core   +1 more source

Secukinumab in the treatment of psoriasis: patient selection and perspectives. [PDF]

open access: yes, 2018
Secukinumab is a human monoclonal antibody targeting IL-17A that has been approved for three indications: moderate-to-severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis.
Beck, Kristen M   +2 more
core   +1 more source

The role of psychological stress in the pathogenesis of psoriasis

open access: yesFrontiers in Medicine
Psoriasis is an immune-mediated dermatosis characterized by systemic inflammation and multifactorial pathogenesis. Among its many triggers, psychological stress has emerged as a pivotal yet underappreciated contributor to disease onset and exacerbation ...
Dongyun Lei   +6 more
doaj   +1 more source

Assessment of Interleukin 16 Serum Levels and Skin Expression in Psoriasis Patients in Correlation with Clinical Severity of the Disease. [PDF]

open access: yesPLoS ONE, 2016
Interleukin 16 (IL-16) has been described as a significant cytokine involved in the recruitment of CD4+ cells during inflammation; however, its potential role in psoriasis has not been defined.
Dorota Purzycka-Bohdan   +7 more
doaj   +1 more source

Bioelectrical phase angle and psoriasis: a novel association with psoriasis severity, quality of life and metabolic syndrome. [PDF]

open access: yes, 2016
Background: Obesity, metabolic syndrome (MetS), and psoriasis, largely driven by environmental factors, show multiple bidirectional associations, with important metabolic implications in psoriatic patients.
BALATO, ANNA   +9 more
core   +1 more source

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