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Infliximab for the treatment of psoriasis
Expert Opinion on Biological Therapy, 2006Psoriasis is a common immune-mediated skin disease producing significant morbidity. Tumour necrosis factor (TNF)-alpha, a pro-inflammatory cytokine, plays a key role in the cutaneous inflammation characteristic of psoriasis. Infliximab is a chimeric monoclonal antibody that specifically binds to TNF-alpha, thereby blocking its biological activity. Data
Kleyn, C. Elise+1 more
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Brodalumab for the treatment of psoriasis
Expert Review of Clinical Immunology, 2016Psoriasis is a complex disease in which the alteration of the IL-23/Th17 axis appears to be crucial for its pathogenic mechanisms, and anti-IL17 agents are rapidly becoming important therapeutic tools. Brodalumab, a fully human Chinese hamster ovary cell-derived immunoglobulin G2 (IgG2) anti-IL-17RA monoclonal antibody, is currently the most-developed ...
Galluzzo, M+3 more
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JAMA: The Journal of the American Medical Association, 1883
[Read before the Philadelphia Country Medical Society, October 17, 1883.] Psoriasis is one of the commoner skin diseases met with in this country. The statistics of the American Dermatological Association show that it occurs in the proportion of about 6 per cent, in all diseases of the skin encountered.
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[Read before the Philadelphia Country Medical Society, October 17, 1883.] Psoriasis is one of the commoner skin diseases met with in this country. The statistics of the American Dermatological Association show that it occurs in the proportion of about 6 per cent, in all diseases of the skin encountered.
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Ustekinumab for the treatment of psoriasis
Expert Review of Clinical Immunology, 2011Management of psoriasis over the last decade has changed significantly with the introduction of biological therapies. Ustekinumab is a first-in-class biological agent, inhibiting the action of IL-12 and IL-23, and has provided further evidence for the role of Th1 and Th17 lymphocytes in the pathogenesis of psoriasis.
Laws, Philip M., Warren, Richard B.
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Topical treatment of psoriasis
Expert Opinion on Pharmacotherapy, 2010The majority of patients with psoriasis can be safely and effectively treated with topical therapy alone, either under the supervision of a family physician or dermatologist. For those requiring systemic agents, topical therapies can provide additional benefit.
Laws, Philip M, Young, Helen S
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Tofacitinib for the treatment of psoriasis
Expert Opinion on Pharmacotherapy, 2016The identification of a number of psoriasis-susceptibility genes and a better understanding of the pathogenesis of the intracellular metabolic pathways, have generated new perspectives on psoriasis treatment, in particular new compounds that inhibit certain intracellular proteins involved in the immune response.
Galluzzo, M+5 more
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The topical treatment of psoriasis
Clinical and Experimental Dermatology, 2005Item does not contain ...
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Photochemotherapy Treatment for Psoriasis
Physical Therapy, 1981Psoriasis is a disease resulting from accelerated replication and abnormal maturation of epidermal cells.1 It has a 1 to 2 percent prevalence in the United States.1 Currently, therapy is merely suppressive. Conventional treatment for psoriasis is the Goeckerman technique, involving the use of tar and ultraviolet B (UVB) (290–320 nm).2 Classically ...
Richard L. Zuehlke, Donald G Shurr
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Treatment of Psoriasis with Riboflavin
Archives of Dermatology, 1958The therapeutic effects of riboflavin in psoriasis have recently been studied by several investigators. Their results are rather varied. Luscombe 1 reported marked improvement in 45% and improvement in 43% of the cases he followed and concluded that this form of therapy was a welcome addition to our armamentarium.
Bencel L. Schiff, Arthur B. Kern
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