Results 181 to 190 of about 38,515 (217)

Biologics reduced infections in ankylosing spondylitis and psoriatic arthritis under immunosuppressants. [PDF]

J Chin Med Assoc
Tung HY, Liao HT, Wang CC, Chen WL, Tsai CY.   +4 more
europepmc   +1 more source

Impact of Selective Tyrosine Kinase 2 Inhibition With Zasocitinib (TAK‐279) on Molecular Pathways and Correlated Clinical Response in Patients With Active Psoriatic Arthritis

ACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective This post hoc analysis evaluated the effect of zasocitinib, an investigational, oral, allosteric, highly selective, and potent tyrosine kinase 2 (TYK2) inhibitor in late‐stage clinical development, on TYK2 signaling response and disease‐related biomarkers and the association of these changes with clinical response in patients with active ...
Amit Choudhury, Jie Cheng, Jay Tang, Sachin Kumar, Banishree Saha, Vinayagam Arunachalam, Ting Hong, Ejim Mark, Håkan Wennbo, Iain B. McInnes   +9 more
wiley   +1 more source

Bilateral knee lipoma arborescens mimicking persistent inflammatory arthritis in a patient with psoriatic arthritis. [PDF]

BMJ Case Rep
Layog BAA, Gonzales JR, Chua JR, Rubio DA.   +3 more
europepmc   +1 more source

Clinical Phenotypes, Treatment, and Outcomes of Rheumatic Immune–Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitors: A Rheumatologists‐Referred Multicenter German Registry Cohort

ACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective Immune checkpoint inhibitors (ICIs) induce a broad range of immune‐related adverse events (irAEs), including rheumatic manifestations. Evidence from dedicated rheumatology cohorts on the clinical spectrum, severity, treatment, and outcomes of rheumatic irAEs (rh‐irAEs) remains limited.
Didzis Gailis, Fabian T.H. Ullrich, Sophia Dombret, Marc Schmalzing, Rebecca Hasseli‐Fräbel, Torsten Witte, Thea Thiele, Uta Kiltz, Mara Oleszowsky, Marcel Müller, Karolina Gente, Christof Specker, Matthias B. Thaler, Alla Skapenko, Hendrik Schulze‐Koops   +14 more
wiley   +1 more source

Arrhythmic risk stratification in psoriatic arthritis: a retrospective, electrogram-based comparative analysis. [PDF]

RMD Open
Sewerin P, Bismpos D, Lange PS, Horstmann N, Sprave H, Ukena C, Baraliakos X.   +6 more
europepmc   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, Volume 13, Issue 49, 3 September 2026.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

Cutaneous Manifestations in Psoriatic Arthritis: Phenotypes, Clinical Burden, and Therapeutic Implications. [PDF]

Rheumatol Ther
Tsafis K, Skepastianos V, Skouvaklidou E, Deligeorgakis D, Boutel M, Kontonikola A, Papazoglou N, Fragoulis GE, Kougkas N.   +8 more
europepmc   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1989-1999, September 2026.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura B. Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore   +19 more
wiley   +1 more source

Evaluating the psychosocial and clinical impact of diagnostic delay in psoriatic arthritis: insights from a monocentric cohort. [PDF]

Front Immunol
Ferrigno S, De Vincenzo F, Panetta M, Arena M, Alessio C, Turri M, Vano L, Prevete I, Sensi F, Contardi A, Sebastiani GD.   +10 more
europepmc   +1 more source

Comment on: Clinical outcomes in psoriatic arthritis patients with rheumatoid factor positivity: Reply. [PDF]

Rheumatology (Oxford)
Mehta P, Kharouf F, Carrizo Abarza V, Gao S, Gladman DD, Chandran V, Poddubnyy D.   +6 more
europepmc   +1 more source