Results 221 to 230 of about 510,697 (405)

Super‐Response to Guselkumab Treatment in Patients With Moderate‐to‐Severe Psoriasis: Real‐World Data With Up to Five Years of Follow‐Up in The Czech Republic

International Journal of Dermatology, EarlyView.
Super‐response to Guselkumab. ABSTRACT Background Guselkumab, a selective interleukin (IL)‐23 inhibitor, is approved for the treatment of moderate‐to‐severe plaque psoriasis. While randomized clinical trials have introduced the concept of “super‐responders” (SRe)—patients achieving complete skin clearance (Psoriasis Area and Severity Index [PASI] 100 ...
Martina Kojanova, Daniela Pejrilova, Jorga Fialova, Petra Cetkovska, Spyridon Gkalpakiotis, Alena Machovcova, Petr Arenberger, Jiri Stork, Tomas Dolezal, Martin Tichy, the BIOREP study group, Zdenek Antal, Monika Balaz, Jirina Bartonova, Gabriela Behrami, Linda Blahova, Petr Bohac, Martin Cetkovsky, Dominika Diamantova, Magdalena Dobiasova, Olga Filipovska, Jana Foldesova, Martina Grycova, Eduard Hrnciř, Jiri Horazdovsky, Katerina Hrazdirova, Monika Hudymacova, Marie Jandova, Hana Janatova, Lucie Jaresova, Ludmila Kajtmanova, Frantisek Keznikl, Peter Kicko, Zuzana Kondasova, Sarka Kozojedova, Jiri Korda, Jana Kreisslova, Anezka Kreisslova, Silvie Krchova, Lenka Kulmanova, Natalie Kunesova, Zdenka Kysilka, Iva Lomicova, Romana Machackova, Barbora Machackova, Lukas Mericko, Miroslav Necas, Helena Nemcova, Radka Neumannova, Michaela Novakova, Jitka Osmerova, Veronika Pallova, Veronika Patavova, Lucie Petrů, Marie Policarova, Tomas Pospisil, Simona Risianova, Filip Rob, Marcela Rozkosova, Libuse Sazmova, Jaroslav Sevcik, Iva Schmidtmayerova, Martin Sicha, Kristyna Sokolova, Eliska Stankova, Jan Sternbersky, Ivana Strouhalova, David Stuchlik, Alena Stumpfova, Katerina Svarcova, Katerina Tepla, Hana Tomkova, Jana Tresnak Hercogova, Simona Vachatova, Yvetta Vantuchova, Ivana Vejrova, Iva Zampachova   +76 more
wiley   +1 more source

Exonic Variation in HLA‐C, CFB, and TAP2 Associated With Increased Risk for Comorbid Crohn's Disease and Psoriasis

International Journal of Dermatology, EarlyView.
Our recent work established an association between high polygenic risk scores (PRSes) for both psoriasis and Crohn's disease with the development of comorbid disease. The protein‐coding genetic variation associated with the development of comorbid psoriasis and Crohn's disease is understudied.
Vikram R. Shaw, Jinyoung Byun, Catherine Zhu, Jared Sninsky, Younghun Han, Jeffrey M. Cohen, Christopher I. Amos   +6 more
wiley   +1 more source

Inflammatory osteolysis: A conspiracy against bone [PDF]

, 2017
Abu-Amer, Abu-Amer, Anton, Bardin, Beranger, Chen, Christo, Claro, Cobelli, Coll, Dapunt, Deborah V. Novack, Dewhirst, Gabriel Mbalaviele, Georg Schett, Gravallese, Harre, Josse, Jovanovic, Kollias, Lukens, Maitra, McCall, Mukai, Negishi-Koga, Osta, Ozen, Pasco, Robaszkiewicz, Rubbert-Roth, Sanchez, Scianaro, Sharma, Steven L. Teitelbaum, Van Hauwermeiren, Wang, Zaki   +36 more
core   +2 more sources

Peripheral corneal melting syndrome in psoriatic arthritis treated with adalimumab

, 2014
Juan Pablo Restrepo, Luis Fernando Medina, María del Pilar Molina   +2 more
openalex   +1 more source

Evaluating Associations Between Ankylosing Spondylitis, Torque Teno Virus and Polymorphisms in Interleukin 6 and Vitamin D Receptor Genes

International Journal of Immunogenetics, EarlyView.
ABSTRACT The etiology of ankylosing spondylitis (AS) is complex and not yet fully understood. Interleukin‐6 (IL‐6), vitamin D and the vitamin D receptor (VDR) play an important role in modulating immune response, and Torque teno virus is considered a marker of immune status. This case–control study aimed to investigate the predisposition to AS. A total
Dănuț Cimponeriu, Lavinia‐Mariana Berca, Irina Radu, Mihai Toma, Remus Nica, Silvia Nica, Roxana Măciucă   +6 more
wiley   +1 more source

The research potential of A20 in psoriatic arthritis. [PDF]

Front Immunol
Wan YW, Duan X, Jin Z, Chen H.
europepmc   +1 more source

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

Immunology, EarlyView.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Therapeutic Windows Across the Psoriatic Arthritis Spectrum. [PDF]

Rheumatol Ther
Kang JH, Coates LC.
europepmc   +1 more source

Psoriatic Arthritis: From Diagnosis to Treatment. [PDF]

J Clin Med
Kannappan R, Kim S, Lau A, Brent LH.
europepmc   +1 more source

Prevalence of circulating CD3CD4CD28 and CD3CD8CD28 cells in ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis

, 2011
Bernd Raffeiner, Christian Dejaco, Christina Duftner, Kullich Werner, Goldberger Christian, C Vega Sandra, Keller Michael, Beatrix Grubeck‐Loebenstein, Michael Schirmer   +8 more
openalex   +1 more source