Results 311 to 320 of about 510,697 (405)

Pharmacokinetic Model Selection for Personalized Infliximab Dosing in IBD

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Infliximab, a monoclonal antibody used for immune‐mediated diseases, shows high interpatient pharmacokinetic variability. Prolonged exposure increases the risk of adverse effects and costs, making dose personalization essential to balance safety, efficacy, and cost‐effectiveness. Population pharmacokinetic models support individualized dosing,
Sahira Chaiben, Peggy Gandia, Thibaut Jamme, Nicolas Congy, Didier Concordet   +4 more
wiley   +1 more source

Impaired cardiorespiratory fitness in psoriatic arthritis: insights from cardiopulmonary exercise testing. [PDF]

RMD Open
Kaerts M, de Vlam K, Lories R, Neerinckx B, Swinnen TW.   +4 more
europepmc   +1 more source

Combined Maxacalcitol/Betamethasone Butyrate Propionate Ointment Possesses Long‐Term Sustained Effects of Inducing Regulatory T Cells and Downregulating the Th17 Response, Even After Discontinuation of Its Application in Imiquimod‐Induced Psoriasiform Dermatitis

The Journal of Dermatology, Volume 53, Issue 1, Page 25-34, January 2026.
ABSTRACT We often experience sustained improvement, even after discontinuation of treatment in psoriasis lesions treated with topical vitamin D3 (VD3) or the combination of topical corticosteroids and VD3. However, the underlying mechanisms of these sustained effects remain unclear. We explored mechanisms for the sustained effects of maxacalcitol (MCT)
Teruo Shimizu, Masahiro Kamata, Hideya Uratsuji, Yoshiki Okada, Ayu Watanabe, Azusa Hiura, Yayoi Tomura, Yayoi Tada   +7 more
wiley   +1 more source

Evaluation of Pan-Immune-Inflammation Value (PIV) as a Predictive Biomarker for Psoriatic Arthritis in Patients with Psoriasis. [PDF]

Clin Cosmet Investig Dermatol
Koç Babayiğit F, Yüceer RO, Babayiğit A, Şahin A.   +3 more
europepmc   +1 more source

Deciphering Pigmented Rice Varieties as Sustainable and Unexplored Valuable Sources of Bioactive Components With Health‐Related Properties and Technological Applications—A Systematic Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT The interest in pigmented grains has grown substantially in recent years. Pigmented rice is crucial for diversifying agricultural production and promoting healthier, more balanced diets. This systematic review updates and discusses literature published between 2019 and 2024 on the bioactive compounds in pigmented rice, their potential health ...
Adolfo Pinheiro de Oliveira, Thatyane Mariano Rodrigues de Albuquerque, Evandro Leite de Souza   +2 more
wiley   +1 more source

Therapeutic strategy in psoriatic arthritis: choosing the right treatment for the right patient. [PDF]

Ther Adv Musculoskelet Dis
Fragoulis GE, Zhao SS.
europepmc   +1 more source

The Association Between Psoriasis, Psoriatic Arthritis, and Fibromyalgia Syndrome: Effects on Treatment-A Population-Based Study. [PDF]

Medicina (Kaunas)
Elizur Y, Amital M, Ben-Shabat N, Patt C, Zacay G, Lassman S, McGonagle D, Watad A, Gendelman O, Amital H.   +9 more
europepmc   +1 more source

How Scalp Trichoscopy Aids in the Diagnosis of Psoriasis in the Setting of Psoriatic Arthritis: Case Report. [PDF]

Skin Appendage Disord
Khutsishvili N, Lortkipanidze M, Buchukuri I, Tkeshelashvili G, Lortkipanidze N.   +4 more
europepmc   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Oral TYK2 Inhibitor D‐2570 in Healthy Subjects: A First‐in‐Human Phase I Study

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT D‐2570 selectively binds to the pseudokinase domain of tyrosine kinase 2, which mediates the downstream cytokine signaling pathways involved in immune regulation. The safety, tolerability, pharmacokinetics, and pharmacodynamics of D‐2570 were evaluated in a randomized, double‐blind, placebo‐controlled phase I study conducted in healthy Chinese
Meng Wang, Quanying Zhang, Zhe Shi, Ling Zhang, Jie Pan   +4 more
wiley   +1 more source