Results 321 to 330 of about 510,697 (405)

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa   +7 more
wiley   +1 more source

Reduced EZH2 Expression in Circulating CD8‐Positive T Cells and Monocytes in Psoriasis

open access: yesExperimental Dermatology, Volume 35, Issue 1, January 2026.
ABSTRACT Enhancer of Zeste Homologue 2 (EZH2) is an epigenetic regulator involved in immune cell differentiation and function; however, its role in psoriasis remains unknown. This study aimed to evaluate EZH2 expression in peripheral blood mononuclear cells from patients with psoriasis and explore its potential functional relevance to disease ...
Toyoki Yamamoto   +5 more
wiley   +1 more source

What Is the Diagnostic Capacity of Existing Severity Scoring Tools for Nail Psoriasis?

open access: yesInternational Journal of Dermatology, Volume 65, Issue 1, Page 86-92, January 2026.
ABSTRACT Background It is challenging to distinguish nail psoriasis (NP) from nonspecific nail changes, contributing to heterogeneity in clinical trials. Existing scoring tools for NP are currently used to assess severity after diagnosis is established.
Evi C. C. Rikken   +5 more
wiley   +1 more source

Dual-platform urinary metabolomics identifies candidate diagnostic biomarkers in Psoriatic Arthritis. [PDF]

open access: yesBiochem Biophys Rep
Peddi K   +8 more
europepmc   +1 more source

Mitochondrial Activity Regulates Human T Helper 17 Differentiation and Function

open access: yesImmunology, Volume 177, Issue 1, Page 185-198, January 2026.
Naïve CD4+ T cells differentiating into RORγt+IL‐17A+ Th17 cells are characterised by a shift from glycolysis to oxidative phosphorylation. Early‐stage cells favour glycolysis, whereas later‐stage cells with hyperpolarised mitochondrial membrane potential (ΔΨ) rely more on oxidative phosphorylation, show increased activation, and differentiate more ...
Xinlai Chen   +10 more
wiley   +1 more source

Variability of Psoriatic Arthritis Impact of Disease questionnaire (PsAID12) thresholds in psoriatic arthritis: data from the ReFlaP study. [PDF]

open access: yesRheumatology (Oxford)
López-Medina C   +24 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy