Results 171 to 180 of about 956,320 (295)
Limited sex‐specific structural alterations across common epilepsies: A worldwide ENIGMA study
Epilepsia, EarlyView.Abstract Objective
Epilepsy is characterized by widespread cortical and subcortical structural alterations beyond the epileptic zone. Importantly, the clinical manifestation of epilepsy, including seizure types, psychiatric comorbidities, and treatment responses, has been shown to differ between sexes. However, sex differences in structural alterations Huantao Wen, Bin Wan, Taha Gholipour, Ke Xie, Judy Chen, Bianca Serio, Meike D. Hettwer, Marina K. M. Alvim, Donatello Arienzo, Rafael Batista João, Tobias Bauer, Andrea Bernasconi, Neda Bernasconi, Paolo Bonanni, Maria Eugenia Caligiuri, Fernando Cendes, Raphaël Christin, Luis Concha, Arielle Dascal, Edward Davoodi Boyd, Orrin Devinsky, Niels K. N. Focke, Francesco Fortunato, Marian Galovic, Antonio Gambardella, Renzo Guerrini, Sean N. Hatton, Mirana Iliza, Sara Inati, Victoria Ives‐Deliperi, Robert‐Paul Juster, Jonathan K. Kleen, Mohamad Z. Koubeissi, Angelo Labate, Sara Larivière, Meng Law, Matteo Lenge, Stefano Meletti, Patrick B. Moloney, Marlo Naish, Alexander Ngo, Terence J. O'Brien, Raluca Pana, Sofia Panzeri, Heath Pardoe, Erik H. U. Rauf, Antonella Riva, Raúl Rodríguez‐Cruces, Jessica Royer, Theodor Rüber, Ella Sahlas, Lucas Scárdua‐Silva, Kai Michael Schubert, Leigh N. Sepeta, Mariasavina Severino, Benjamin Sinclair, Hamid Soltanian‐Zadeh, Travis Stoub, Pasquale Striano, Sophia I. Thomopoulos, Nina V. Valientes, Anna Elisabetta Vaudano, Lucy Vivash, Clarissa L. Yasuda, Paul M. Thompson, Sanjay M. Sisodiya, Carrie R. McDonald, Boris C. Bernhardt, Sofie L. Valk +68 morewiley +1 more sourceNon‐contrast MRI reliably captures perfusion abnormalities in status epilepticus
Epilepsia, EarlyView.Abstract Objective
To determine whether non‐contrast pseudo‐continuous arterial spin labeling (pCASL) detects status epilepticus (SE)–related perfusion abnormalities and shows quantitative correspondence with dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging (MRI), and to compare single‐slice and volumetric approaches for ...Lukas Machegger, Pilar Bosque‐Varela, Jürgen Steinbacher, Johannes Pfaff, Eugen Trinka, Giorgi Kuchukhidze +5 morewiley +1 more sourcePrognosis of acute symptomatic seizures and impact of prolonged treatment with anti‐seizure medication
Epilepsia, EarlyView.Abstract Objectives
Acute symptomatic epileptic seizures (ASySs) occur in temporal proximity to acute brain insults. Given their low risk of subsequent unprovoked seizures, current guidelines recommend either no treatment with anti‐seizure medication (ASM) or early discontinuation, yet ASM treatment is often continued beyond hospital discharge.Hannah Traben, Julia Herzig‐Nichtweiß, Lisa Langenbruch, Felix Kohle, Johann O. Pelz, Piergiorgio Lochner, Matthias Wittstock, Albrecht Günther, Angelika Alonso, Marko Blickhan, Silvia Schönenberger, Sascha Berning, Michael P. Malter, Annekatrin Müller, Frauke Röll, Waldemar Gubarev, Kai M. Schubert, Marian Galovic, Maximilian Mönch, Ulrike Grittner, Martin Holtkamp, Farid Salih, Bernd J. Vorderwülbecke, for the IGNITE! Study Group +23 morewiley +1 more sourceMultimodal modeling of the ictal onset zone in refractory insular epilepsy and seizure outcome of magnetic resonance‐guided laser interstitial therapy: A pediatric single‐center retrospective study
Epilepsia, EarlyView.Abstract Objective
This study was undertaken to evaluate seizure outcomes after magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) in children with insular epilepsy and to assess how the extent of ablation overlaps with multimodal definitions of the ictal onset zone (IOZ).Lelio Guida, Emma Losito, Sebastian Rodrigo, Catherine Chiron, Ludovic Fillon, Marie Bourgeois, Anna Kaminska, Johan Pallud, Nicole Chemaly, Volodia Dangouloff‐Ross, Stephane Auvin, Blandine Dozieres, Rima Nabbout, Olivier David, Nathalie Boddaert, Thomas Blauwblomme +15 morewiley +1 more sourceImpairment of ictal consciousness and psychosis in drug‐resistant focal epilepsy: A retrospective clinical cohort study
Epilepsia, EarlyView.Abstract Objective
Psychoses of epilepsy (POE) affect up to 13% of patients with focal epilepsy. Whereas interictal risk factors are well documented, ictal correlates of POE remain poorly characterized. We hypothesized that an impairment of ictal consciousness on the Consciousness Seizure Scale (CSS), would be associated with POE.Alexis Tarrada, Coraline Hingray, Olivier Aron, Clélia Galmiche, Louis Maillard, Marco Mula, Bertrand De Toffol, Cédric Baumann, Sophie Baltassis +8 morewiley +1 more sourceLongitudinal serum and CSF cytokine dynamics in NORSE: Associations with immunotherapy exposure
Epilepsia, EarlyView.Abstract Objective
To characterize serum and cerebrospinal fluid (CSF) cytokine dynamics according to immunotherapy exposure in cryptogenic new‐onset refractory status epilepticus (cNORSE). Methods
We analyzed cytokine profiles in 94 serum and 42 CSF samples from 29 and 14 patients, respectively, with cNORSE.Aurélie Hanin, Clémence Marois, Léa Cosme, Quentin Calonge, Zineb Hayatou, Sarah Baer, Anna‐Lena Behr, Simone Beretta, Francesca Bisulli, Serena Broggi, Michael Cardinale, Carlos Castillo‐Pinto, Adam Celier, Thomas Coppens, Anne De Saint Martin, Krista Eschbach, Susana Ferrao Santos, Elizabeth E. Gerard, Teneille Gofton, Margaret T. Gopaul, Karnig Kazazian, Jeroen Kerstens, Humberto L. Moser Filho, Lorenzo Muccioli, Roberto Santalucia, Hannah Stamberger, Eyal Muscal, Lawrence J. Hirsch, Sophie Demeret, Vincent Navarro +29 morewiley +1 more sourceQuantification of peri‐ictal magnetic resonance imaging abnormalities (PMA) in status epilepticus: Clinical and prognostic significance of PMA volume
Epilepsia, EarlyView.Abstract Objective
Peri‐ictal magnetic resonance imaging (MRI) abnormalities (PMA) are increasingly recognized in patients with status epilepticus (SE), but the clinical factors influencing their occurrence and extent remain incompletely understood. We aimed to quantify PMA and investigate the associations of PMA occurrence and volume with SE duration, Clara Jünemann, Marcus Belke, Emily Falk, Pilar Bosque‐Varela, Anna Wieacker, Payam Tabaee Damavandi, Leona Möller, Wiebke Hahn, André Kemmling, Lars Timmermann, Lukas Machegger, Eugen Trinka, Giorgi Kuchukhidze, Susanne Knake, Panagiota‐Eleni Tsalouchidou +14 morewiley +1 more source