Results 151 to 160 of about 302,264 (197)
Abstract Background Parkinson's disease (PD) places a high burden on patients, their families, healthcare systems, and society as a whole, which is rising due to the increasing prevalence of PD. There has been wide variation in the items included in previous cost of illness (COI) studies for PD, possibly underestimating the costs associated with this ...
Anke Wijers+3 more
wiley +1 more source
Increase of Plasma Biomarkers in Friedreich's Ataxia: Potential Insights into Disease Pathology
Abstract Background Therapeutic interventions in Friedreich's ataxia (FRDA) are progressing into clinical trials, and the need for robust and easily accessible biomarkers has arisen. Objective This study aimed to consolidate preliminary findings of changes in the levels of neurofilament light (NfL), glial fibrillary acidic protein (GFAP), Tau, and ...
Christian Rummey+9 more
wiley +1 more source
Quality of Life of People With Neuromuscular Diseases: The Role of Stigma
ABSTRACT Introduction/Aims Stigma is thought to have a profound impact on quality of life (QoL) among people with neuromuscular diseases (NMD), but empirical evidence is limited. This study sought to explore associations of enacted stigma (social exclusion) and felt stigma (shame, fear of exclusion) with QoL.
Marion Sommers‐Spijkerman+5 more
wiley +1 more source
Abstract Objective The objective of this study was to investigate whether long‐term weight change in children with obesity is affected after deciding not to participate in a lifestyle intervention. Methods This observational study included 713 children (aged 5–8 years) with obesity living in Aarhus, Denmark, of whom 157 decided not to participate in a ...
Rasmus M. Jørgensen+5 more
wiley +1 more source
Abstract Objective Timely initiation of postoperative radiotherapy (PORT) for head and neck squamous cell carcinoma (HNSCC) is associated with improved survival, but rates of timely PORT initiation are low. To support uptake in a tertiary academic center, we aimed to identify implementation determinants (eg, barriers and facilitators) to timely PORT ...
Laila A. Gharzai+11 more
wiley +1 more source
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas+8 more
wiley +1 more source
ABSTRACT The psychological distress among manufacturing workers is an increasingly important issue and has attracted extensive attention. However, the mental health of this subgroup of the Chinese population is underexplored. This study aimed to evaluate the prevalence of psychological distress in Chinese manufacturing employees and identify central ...
Jie Meng, Xueping Meng
wiley +1 more source
Psychiatric Emergency or General Emergency: Evolution or Involution? A Qualitative Study With Mental Health and Emergency Professionals. [PDF]
Alberto CC, Silvia Z.
europepmc +1 more source