Results 71 to 80 of about 916,311 (314)
Brain‐Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety‐Like Behaviors in Mice
J.Liu et al. reveal the complete propagation dynamics of cortical traveling waves, from local circuitry initiation to long‐range propagation, and identify their functional relevance in modulating anxiety‐like behaviors and underlying cellular neuroplasticity in mice.
Jiaming Liu+15 more
wiley +1 more source
Making Sense of Kleptomania: Clinical Considerations
An understanding of the historical roots, clinical features and current diagnostic criteria of kleptomania would help in a better appreciation and assessment of this condition. One of the few psychiatric conditions that is defined by an illegal activity,
Kuan Tsee Chee MBBS, MRCPsych, FAMS+3 more
doaj +1 more source
Manual of Psychiatry and Mental Hygiene. [PDF]
Winfred Overholser, Aaron J. Rosanoff
+4 more sources
Network Desynchronization with Sine Waves: from Synchrony to Asynchrony by Periodic Stimulation
Exogenous alternating current fields are explored and interact with cerebral cortex slow waves in vitro and in silico. Varying frequency and amplitude of sine waves result in distinct network dynamics, from phase‐locking and entrainment to desynchronization. These responses occupy specific regions within the parameter space.
Joana Covelo+4 more
wiley +1 more source
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia+29 more
wiley +1 more source
Background A Sri Lankan university recently changed its medical undergraduate curriculum by including a multifaceted psychiatry clerkship for final year students.
Asiri Rodrigo+2 more
doaj +1 more source
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song+24 more
wiley +1 more source
Preventive psychiatry: Current status in contemporary psychiatry
Preventive psychiatry is one of the most ignored subdiscipline of psychiatry, which has got important role to play in the contemporary psychiatry. Mental disorders are very common with lifetime prevalence of about 25%, and tend to be chronic.
Rakesh Kumar Chadda
doaj +1 more source
Aging and the Spectral Properties of Brain Hemodynamics
As the brain ages, its metabolic demands decline—but not uniformly. Here, spectral slope flattening of resting‐state fMRI signals is proposed as a potential biomarker of pathologic brain aging. A subset of older adults diverges from youthful spectral and metabolic patterns, with changes linked to frontal white matter pathology and regional loss of ...
Ki Yun Park+9 more
wiley +1 more source