This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma +16 more
wiley +1 more source
The effects of perceived social support and psychological capital on attitudes towards professional psychological help-seeking among Chinese college students: The mediating role of psychological help-seeking stigma. [PDF]
Xie Y, Yao L, Ye C.
europepmc +1 more source
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan +11 more
wiley +1 more source
Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini +8 more
wiley +1 more source
The mediating role of psychological well-being in the relationship between psychosocial health and psychological resilience in expectant women. [PDF]
Gençarslan DÖ +5 more
europepmc +1 more source
Multi‐Functional Adaptive Interfaces for Next‐Generation Wearable and Implantable Bioelectronics
Adaptive Biointerfaces: A comprehensive overview of next‐generation bioelectronics is presented, highlighting mechano‐adaptive and biophysiologically adaptive interfaces that enable stable, long‐term integration with living tissues. As illustrated in the image, adaptive interface strategies, including mechano‐adaptivity (e.g., injectability, shape ...
Jinhong Park +7 more
wiley +1 more source
Psychological Safety as a Predictor of Acute Stress, Well-Being and Burnout in Health and Social Care Workers: A Predictive Correlational Study. [PDF]
Cogan N, Smith M, Deakin K.
europepmc +1 more source
Distinct Biotypes of Visual Perception in Major Depressive Disorder
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai +13 more
wiley +1 more source
The relationship between live streamers' self-disclosure and consumers' purchase intention: The parallel mediating role of psychological distance and perceived homophily. [PDF]
Liu Y.
europepmc +1 more source

