Results 71 to 80 of about 160,419 (261)

Comparative analysis of psychological adaptation in patients with paranoid schizophrenia and shizotypal disorder

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2015
The purpose of this research was the comparing of psychological adaptation characteristics (type of attitude to a disease, psychological defense mechanisms, special aspects of coping-strategy) as exemplified by 2 groups of schizophrenia disorder patients:
A. V. Stepanova
doaj   +1 more source

Advancing Dry Electroencephalography With Scalable, Soft, and Transcranial Magnetic Stimulation‐Compatible Ti3C2Tx MXene Electrodes for Research and Clinical‐Grade Applications

open access: yesAdvanced Science, EarlyView.
Dry soft Ti3C2Tx MXene electroencephalography (EEG) electrodes provide low impedance (2.1 ± 1.8 kΩ at 10 Hz), long‐term stability, and enable safe simultaneous EEG and transcranial magnetic stimulation (TMS). Across scalp sites, hair types, and recording paradigms, including steady state visual evoked potentials (SSVEP), clinical EEG, and mobile EEG ...
Sneha Shankar   +17 more
wiley   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

open access: yesAdvanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag   +3 more
wiley   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

Respiratory‐Limbic Coupling via a Thalamic Circuit Alleviates Anxiety

open access: yesAdvanced Science, EarlyView.
This study delineates a conserved preBötCGlu→PVT→CeA circuit that gates anxiety and respiration. Activation of this circuit is anxiolytic and respiratory‐stabilizing, while its inhibition has the opposite effect. Mechanistically, PVT exerts its anxiolytic action via a disinhibitory microcircuit: its inputs preferentially target CeL GABAergic neurons ...
Shangyu Bi   +15 more
wiley   +1 more source

H2S‐Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety

open access: yesAdvanced Science, EarlyView.
Albumin nanoparticles loaded with an H2S‐releasing aspirin derivative (ACS14) hitchhiking neutrophils after intraperitoneal injection and preferentially accumulate in endometriosis lesions in mice. The treatment suppresses lesion growth by regulating PI3K/Akt and reduces inflammation by inhibiting NF‐κB.
Mengni Zhou   +12 more
wiley   +1 more source

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

open access: yesAdvanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma   +16 more
wiley   +1 more source

Strategies among Students of Guilan University of Medical Sciences

open access: yesJournal of Holistic Nursing and Midwifery, 2014
Introduction: Stress is an undeniable fact of human life and is known as one of most important causes of diseases therefore response to stress can have important role in adaptation.
MAryam Niknami   +4 more
doaj  

Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity

open access: yesAdvanced Science, EarlyView.
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini   +8 more
wiley   +1 more source

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