Results 191 to 200 of about 2,894,762 (299)

Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium

Advanced Science, EarlyView.
Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed, Zicheng Deng, Arnab Misra, Marcus Orzabal, Ananya Kondapally, Enhong Li, Jonathan Do, Ying‐Wei Lan, Fatemeh Kohram, Hunter Blackburn, Andreas Damianos, Tanya V. Kalin, Vladimir V. Kalinichenko   +12 more
wiley   +1 more source

Academic achievement of peer group leaders and members: Contributions to adolescents' social, school, and psychological adjustment. [PDF]

J Res Adolesc
Zhou J, Chen X, Li D, Liu J, Cui L, Liu S.   +5 more
europepmc   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

Nature nurtures our wellbeing: primary emotions and attachment mediate our psychological adjustment via connectedness to nature. [PDF]

Front Cognit
Quelhas Martins A, Fonte J, Torres N, Ferrajão P.   +3 more
europepmc   +1 more source

Propofol Modulates Fear Memory Reconsolidation by Inhibiting D2 Receptor‐Expressing Neurons in the Medial Prefrontal Cortex

Advanced Science, EarlyView.
This study shows that propofol modulates fear‐memory reconsolidation in mice. It works by suppressing D2 receptor‐expressing neurons within the medial prefrontal cortex and their connections to the basolateral amygdala. D2‐receptor agonists reproduce this fear‐reducing effect, offering potential non‐anesthetic therapeutic strategies for trauma‐related ...
Jie Li, Yi‐Ge Guo, Xing Xu, Gui‐Lin Meng, Han Li, Liu‐Wei Chu, Xin‐Yuan Chen, Xiao‐Yun Guo, Tao Xu, Ti‐Fei Yuan, Ji Hu, Xiao‐Na Zhu   +11 more
wiley   +1 more source

Psychological adjustment, HIV knowledge, and antiretroviral treatment adherence in newly diagnosed HIV patients: a cross-sectional study from an Albanian infectious diseases clinic. [PDF]

AIDS Res Ther
Hafizi S.
europepmc   +1 more source

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

Advanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau, John J. Foxe, Shlomit Beker, Sophie Molholm   +3 more
wiley   +1 more source

Gel‐Free Capture of Microvolt‐Level Neural Signatures Via a 3D Monolithic Carbon Fiber Dry Electrode

Advanced Science, EarlyView.
A compressible carbon fiber/PEDOT:PSS electrode enables gel‐free contact at hairy scalp sites. Its conductive porous framework supports low interfacial impedance and retains contact performance after repeated mechanical and sweat‐related challenges.
Haoxuan Sun, Nikolay Novitskiy, Dongwook Jang, Yixiang Liu, Shaoqi Pan, Ting Huang, Yitong Li, Huisi Yang, Leonardo Nicholas Adi Wijaya, Md Masruck Alam, Patrick CM Wong, Zhaoli Gao   +11 more
wiley   +1 more source