Results 131 to 140 of about 2,950,482 (310)

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan   +10 more
wiley   +1 more source

Distinct Biotypes of Visual Perception in Major Depressive Disorder

open access: yesAdvanced Science, EarlyView.
In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai   +13 more
wiley   +1 more source

Impact of psychological factors on the final clinical outcomes of patients undergoing ankle arthrodesis and ankle replacement

open access: yesFrontiers in Psychiatry
ObjectiveThis study aims to analyze the impact of different surgical procedures on the prognosis and psychological state of patients with end-stage ankle arthritis (ESAA) by comparing two groups of patients with ESAA who have undergone total ankle ...
Hongze Wang   +4 more
doaj   +1 more source

Space stations: Living in zero gravity, developmental task for psychologists and space environmental experts [PDF]

open access: yes
The recent advances in the psychological aspects of space station design are discussed, including the impact of the increase in awareness of both the public in general as well as space environmental experts of the importance of psychological factors when
Ludwig, E.
core   +1 more source

Factors Contributing to Psycho-Social Ill-Health in Male Adolescents [PDF]

open access: yes, 2011
Objective: To study the prevalence of psychosocial problems in male adolescents and find out various factors contributing to psycho-social ill health.
Chhabra, GS, Sodhi, MK
core   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

Rorschach Indications of Emotional Instability and Susceptibility to Motion Sickness [PDF]

open access: yes
Psychological testing of emotional factors in susceptibility to motion ...
Graybiel, A., Mc Michael, A. E.
core   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

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