Results 121 to 130 of about 1,399,367 (298)

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

Advanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu, Philippa J. Karoly, Sina Mansour L., Artemio Soto‐Breceda, Levin Kuhlmann, Mark J. Cook, David B. Grayden   +6 more
wiley   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

The Relationship of Practical Commitment to Religious Beliefs and Psychological Hardiness with Job Burnout Experienced by Teachers in Special Needs Schools of Children in Kerman in 2015

پژوهش در دین و سلامت, 2020
For downloading the full-text of this article please click here. Background and Objective: Exceptional education teachers are in a very stressful working environment, which is the cause of burnout.
Mohamadreza Babaei, Masoumeh Sadat Sajjadi, Ghasem Askarizadeh   +2 more
doaj  

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

A Study of the Relationships between Family Functioning and Psychological Hardiness among Parents with Exceptional Children and Normal Children

Iranian Rehabilitation Journal, 2012
Objectives: The objective behind this study was investigating the relationships between family functioning and psychological hardiness in parents of exceptional children versus parents of normal children.
Zeinab Golpich, Ali Akbar Soleymanian, Hamid Darudi   +2 more
doaj  

Psychological predictors of human hardiness formation

, 2016
The relevance of the researched problem is conditioned by the growing social and psychological tension in the ever-changing post-industrial society and psychoemotional disorders affecting the human lifespan, developing on this background. The goal of the article is to disclose and analyse psychological predictors of hardiness formation, stipulating ...
Zeer, E. F., Yugova, E. A., Karpova, N. P., Trubetskaya, O. V.   +3 more
openaire   +2 more sources

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source

The psychological bases for personal hardiness increasing [PDF]

У статті викладено психологічні основи підвищення життєстійкості особистості. Виявлено взаємозв’язок життєстійкості особистості із її мотиваційно-смисловими утвореннями та самоставленням.
Купрєєва, О.І., Сердюк, Л.З.   +1 more
core  

Hardiness levels of professional spanish firefighters [PDF]

, 2013
Personality ...
Juan Gómez, Roberto Ruiz, Rivera Rodriguez, Oswaldo, Vega Marcos, Ricardo de la   +2 more
core   +1 more source