Results 151 to 160 of about 4,653,289 (297)

Parabiosis, Assembloids, Organoids (PAO)

open access: yesAdvanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong   +5 more
wiley   +1 more source

Psychological Aspects of Obese Primary School Children Pre- and Post-MyBFF@school Intervention Programme: A Pilot Study

open access: diamond, 2017
Zahari Ishak   +7 more
openalex   +1 more source

A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness

open access: yesAdvanced Science, EarlyView.
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger   +17 more
wiley   +1 more source

Self‐Assembled Dictamni Cortex Nanoparticles Ameliorate Psoriasis by Epigenetic Modulation of HSP90AB1 and Suppression of the Inflammatory Response

open access: yesAdvanced Science, EarlyView.
This study develops self‐assembled Dictamni Cortex (BXP)‐Fe(III) infinite coordination polymer nanoparticles (NB) to improve BXP's solubility and bioavailability for psoriasis. NB transdermally treats psoriasis by targeting the epigenetic regulator CTCF (CCCTC‐binding factor), suppressing HSP90AB1 (heat shock protein 90 alpha family class B member 1 ...
Zhengyi Zhang   +15 more
wiley   +1 more source

The Adaptive Physical Activity Study in Stroke (TAPAS): A Feasibility Sequential Multiple Assignment Randomized Trial

open access: yesAdvanced Science, EarlyView.
This study examines the feasibility of a mobile health physical activity intervention for individuals post‐stroke using a sequential multiple assignment randomized trial (SMART) design. High recruitment, retention, and adherence rates are observed, with promising trends in step count, fatigue, and quality of life.
Aoife Whiston   +20 more
wiley   +1 more source

Functional, Pharmacogenomic, and Immune Landscapes of Long Non‐Coding RNAs in Cancer

open access: yesAdvanced Science, EarlyView.
A systematic analysis of 33 cancer types reveals widespread associations between lncRNAs and cancer pathways, drug responses, immune features, and immunotherapy outcomes. The study identifies key lncRNAs linked to therapeutic response and adverse events and introduces PILNC, an interactive web portal for exploring the functional, pharmacogenomic, and ...
Runhao Wang   +15 more
wiley   +1 more source

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