Results 71 to 80 of about 4,435,161 (296)
The ICH E9(R1) Addendum on Estimands and Sensitivity Analysis provides a framework for defining the treatment effect a trial intends to estimate—the estimand. The addendum is widely adopted in pharmaceutical research. However, it remains underutilized in
Manuel Heinrich +4 more
doaj +1 more source
Background: Childbirth-related posttraumatic stress symptoms (CB-PTSS) have been recognized as a serious postpartum complication. Although childhood maltreatment (CM) is a well-established vulnerability factor for stress-related mental disorders ...
Meike K. Blecker +9 more
doaj +1 more source
Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai +7 more
wiley +1 more source
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij +11 more
wiley +1 more source
Background Sexual problems and well-being are critical areas of mental health that remain under-addressed in traditional psychotherapeutic settings. From a patient’s view, reasons include feelings of discomfort and fear of stigma.
Friederike Fenski +14 more
doaj +1 more source
This work discusses two theses that entail a deep rethinking of both psychological theory and practice. First, it is claimed that General Theory of Psychological Intervention (GTPI) is needed, namely an epistemological framework grounding the modelistic ...
SALVATORE, Sergio, Salvatore Sergio
core
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah +4 more
wiley +1 more source
Psychological intervention improves life quality of patients with laryngeal cancer
Xiaoli Li,1 Jingjing Li,2 Yanxia Shi,2 Ting Wang,2 Aling Zhang,2 Na Shao,2 Zhenghui Wang2 1Department of Dermatology, 2Department of Otolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Xi’an Jiaotong University, Xi’an ...
Shi YX +6 more
core
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni +4 more
wiley +1 more source

