Results 71 to 80 of about 454,139 (263)

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

Advanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu, Philippa J. Karoly, Sina Mansour L., Artemio Soto‐Breceda, Levin Kuhlmann, Mark J. Cook, David B. Grayden   +6 more
wiley   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Internet-based transdiagnostic treatment for emotional disorders in Arabic- and Farsi-speaking refugees: study protocol of a randomized controlled trial

Trials
Background Refugee populations have an increased risk for mental disorders, such as depression, anxiety, and posttraumatic stress disorders. Comorbidity is common.
Johanna Boettcher, Manuel Heinrich, Maria Boettche, Sebastian Burchert, Heide Glaesmer, Euphrosyne Gouzoulis-Mayfrank, Carina Heeke, Martina Hernek, Christine Knaevelsrud, Alexander Konnopka, Louisa Muntendorf, Hannah Nilles, Laura Nohr, Steffi Pohl, Sophia Paskuy, Isabelle Reinhardt, Susan Sierau, Nadine Stammel, Christina Wirz, Babette Renneberg, Birgit Wagner   +20 more
doaj   +1 more source

Dysregulation of Oral Microbial Eicosapentaenoic Acid Induced by Chronic Restraint Stress Exacerbates Periodontitis via M1 Macrophage Polarization

Advanced Science, EarlyView.
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo, Fangzhi Lou, Peiran Yang, Yu Zhang, Li Yan, Yunmei Dong, Bing Yang, Haiyang Wang, Yiyun Liu, Juncai Pu, Richard D. Cannon, Peng Xie, Ping Ji, Xin Jin   +13 more
wiley   +1 more source

Correction: A comparison of interpreters’ wellbeing and work-related characteristics in the care of refugees across different work settings

BMC Public Health, 2022
Angelika Geiling, Maria Böttche, Christine Knaevelsrud, Nadine Stammel   +3 more
doaj   +1 more source

Jobs that suit women: A mixed-methods study of Chinese college women’s perceived benevolent sexism, career aspirations, and career-exploration behaviors

BMC Psychology
Background Benevolent sexism (BS) may implicitly influence women’s career trajectories. This study examined the relationship between Chinese college women’s BS attitudes and experiences, their career aspirations and exploration behaviors, and the ...
Qing Wang, Qinyue Zhu, Jingxin Li, Rongrong Yang   +3 more
doaj   +1 more source

Mechanisms of change in naturalistic mental health care settings: study protocol for a longitudinal multimethod study

BMJ Open
Introduction Mental disorders are among the leading causes of the global burden of disease and are often associated with severe functional impairment and high societal costs.
Christine Knaevelsrud, Maria Böttche, André Kerber, Annette Brose, Phileas Heim, Eva M J Peters, Johannes C Ehrenthal   +6 more
doaj   +1 more source

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source

Transcranial direct current stimulation targeting the bilateral IFG alters cognitive processes during creative ideation

npj Science of Learning
This study investigated whether transcranial direct current stimulation (tDCS) targeting the inferior frontal gyrus (IFG) can alter the thinking process and neural basis of creativity.
Cong Xie, Shuangfei Zhang, Xinuo Qiao, Ning Hao   +3 more
doaj   +1 more source