Results 131 to 140 of about 14,991,528 (336)

Independent Educational Evaluations as Issues of Dispute in Special Education Due Process Hearings [PDF]

open access: yes, 2019
This study examined the pertinent details and outcomes of special education due process hearings (n = 100) that addressed independent educational evaluations as an issue of dispute in a 14-state sample.
Blackwell, William H, Gomez, Mertie
core   +1 more source

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

open access: yesAdvanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai   +13 more
wiley   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

open access: yesAdvanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao   +6 more
wiley   +1 more source

Nietzsche’s polychrome exemplarism [PDF]

open access: yes, 2018
In this paper, I develop an account of Nietzschean exemplarism. Drawing on my previous work, I argue that an agent’s instincts and other drives constitute her psychological type. In this framework, a drive counts as a virtue to the extent that it is well-
Alfano, Mark
core   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

open access: yesAdvanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai   +12 more
wiley   +1 more source

Subject Types of Forensic Psychological Examination Assigned in Connection with Phone Fraud

open access: yesТеория и практика судебной экспертизы
Characteristics of the mental (psychological) state of the victims of criminals presented in this article was based on the analysis of the practice of forensic psychological and complex forensic psychological and psychiatric examinations related to phone
F. S. Safuanov   +3 more
doaj   +1 more source

An Analysis of Theme and Rheme Used in the Five-star Hotels' Web Sites in Surabaya [PDF]

open access: yes, 2017
The study done by the writer observes the themes and rhemes used in the five-star hotels' web sites in Surabaya. It includes the types of themes and the notions of subject which are under the Systemic Functional Grammar (SFG) proposed by Halliday and ...
Gunawan, S. (Samuel)   +1 more
core  

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

open access: yesAdvanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang   +22 more
wiley   +1 more source

Product-Related Risk and Cognitive Biases: The Shortcomings of Enterprise Liability [PDF]

open access: yes, 2000
Products liability law has witnessed a long debate over whether manufacturers should be held strictly liable for the injuries that products cause. Recently, some have argued that psychological research on human judgment supports adopting a regime of ...
Henderson, James A., Jr.   +1 more
core   +2 more sources

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