Results 261 to 270 of about 8,321,560 (344)

The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain

Animal Models and Experimental Medicine, EarlyView.
Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani, Hao Li, Panpan Guo, Qiulin Zhang, Mahmoud M. Abouelfetouh, Mingxing Ding, Yi Ding   +6 more
wiley   +1 more source

The "LLM World of Words" English free association norms generated by large language models. [PDF]

Sci Data
Abramski K, Improta R, Rossetti G, Stella M.   +3 more
europepmc   +1 more source

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

Animal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang, Wei Li, Weiwen Zheng, Jinwen Liu, Nuonan She, Xia Chen, Weibo Wen   +6 more
wiley   +1 more source

Editorial: Insights in consciousness research, volume II. [PDF]

Front Psychol
D'Angiò M, Simione L, Arsiwalla XD, Raffone A.   +3 more
europepmc   +1 more source

Comparative analysis of short‐term and long‐term LL‐37‐induced rosacea‐like mouse models: Histopathological features and inflammatory immune responses

Animal Models and Experimental Medicine, EarlyView.
The aim of this study was to improve the long‐term LL‐37 mouse model and compare the disease manifestations and pathophysiology of short‐term and long‐term LL‐37‐induced rosacea‐like models. The results show that the long‐term LL‐37 induced mouse model provides a practical animal model for further study of the pathological mechanism of severe rosacea ...
Yiling Wu, Chuanxi Zhang, Hui Jin, Ruiping Zheng, Tian Li, Fuyu Jin, Yaqian Li, Xuemin Gao, Hong Xu, Zhongqiu Wei, Jie Yang   +10 more
wiley   +1 more source

Technology-enhanced practice competencies: scoping review and novel model development. [PDF]

Front Digit Health
Perle JG, Chandran DN, Brezler E, Coleman M, Deziel J, Nahhas P, McDonald G, Jent JF.   +7 more
europepmc   +1 more source

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features

Annals of Neurology, EarlyView.
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner, Eliza Honybun, Melanie Bahlo, Karen L. Oliver, Ingrid E. Scheffer   +4 more
wiley   +1 more source

New Transferrin Receptor‐Targeting Conjugate Effectively Delivers DNA to Mouse Brain

Angewandte Chemie, EarlyView.
We present a novel RNA aptamer targeting the transferrin receptor (TfR), conjugated with DSPE lipid, which achieves remarkably efficient brain uptake, reaching brain‐to‐serum ratios as high as 6.5. Through fluorescence imaging and polymerase‐chain reaction analyses, we verify that this new conjugate successfully delivers a substantial amount of DNA ...
Min‐sun Song, Adrian H. Bustos, Lise Bastue, Justas Mikutavicius, Piotr Swiderski, Kelly J. Clemens, Nagy Habib, John Rossi, Kira Astakhova   +8 more
wiley   +2 more sources

A Transdiagnostic Network Analysis of Childhood Trauma and Psychopathology. [PDF]

Schizophr Bull
Huang YH, Liu C, Zhang JB, Li SB, Wang LL, Hu HX, Cai Y, Zhu Z, Chu MY, Wang Y, Lv QY, Lui SSY, Yi ZH, Hui L, Chan RCK.   +14 more
europepmc   +1 more source

Cognitive Outcome in Young Adults after Resolution of Epilepsy in Childhood

Annals of Neurology, EarlyView.
Self‐limited epilepsies of childhood are common and were considered benign. We aim to determine whether cognitive function in young adults who experienced epilepsy as children and are subsequently seizure‐free and unmedicated differ from the general population. We report on a cross‐sectional population‐based study including 2,124,871 men and women aged
Jacob Megreli, Leo Arkush, Estela Derazne, Arnon Afek, Gilad Twig, Bruria Ben‐Zeev, Jaana Ahonniska Assa, Gali Heimer   +7 more
wiley   +1 more source