Results 51 to 60 of about 2,387,414 (178)

Pruritus Is Frequent and Persistent and Impacts Quality of Life Among Patients With Primary Sclerosing Cholangitis

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 9, Page 1288-1297, November 2026.
Among 200 patients with primary sclerosing cholangitis, 38% reported moderate to severe pruritus in the past 6 months. During 6 months of follow up, pruritus severity fluctuated significantly. Pruritus severity was linked to worse colitis activity and lower quality of life.
Richard Dean, Maryam Yazdanfar, Joseph Zepeda, Isha J. Patel, Cynthia Levy, Craig Lammert, Raghav Bordia, Duru Cosar, Katherine Specht, Daniel Pratt, Stuart C. Gordon, Lisa Forman, Fawzy Barry, Michael Li, Usha Gungabissoon, Megan M. McLaughlin, Christopher L. Bowlus   +16 more
wiley   +1 more source

Ammonia, infection and inflammation in hepatic encephalopathy. [PDF]

, 2007
For over a century, we have known that ammonia is important in the pathogenesis of hepatic encephalopathy. Studies in patients with acute liver failure have shown rapid progression to severe encephalopathy in those patients with evidence of a systemic ...
Shawcross, D.L., Shawcross, Deborah Lindsay   +1 more
core  

Glymphatic System Dysfunction and its Associated Factors in Wilson's Disease: A DTI–ALPS Study

Brain and Behavior, Volume 16, Issue 10, October 2026.
Glymphatic function, assessed by DTI‐ALPS index, was impaired in neurological Wilson's disease compared with hepatic phenotype and controls. Age, AST, and UWDRS‐I score independently predicted dysfunction, linking neurodegeneration, liver injury, and altered glymphatic activity. ABSTRACT Background Wilson's disease (WD) is a genetic disorder of copper (
Ling Zhu, Tong Wu, Liang‐Jie Zhang, Qin‐yuan Liu, Liang‐liang Zhang, Bin Song, Yu‐long Zhu, Lei Hua, Long Zhang, Bo Li, Quan Sun, Ben‐chun Xue, Yin Xu, Yong‐zhu Han, Yong‐sheng Han   +14 more
wiley   +1 more source

Automatic Video-Oculography System for Detection of Minimal Hepatic Encephalopathy Using Machine Learning Tools

Sensors, 2023
This article presents an automatic gaze-tracker system to assist in the detection of minimal hepatic encephalopathy by analyzing eye movements with machine learning tools.
Alberto Calvo Córdoba, Cecilia E. García Cena, Carmina Montoliu   +2 more
doaj   +1 more source

Evaluation of IL‐6 for Stepwise Diagnosis of Minimal Hepatic Encephalopathy in Patients With Liver Cirrhosis

Hepatology Communications, 2022
Diagnosis of minimal hepatic encephalopathy (MHE) requires psychometric testing, which is time‐consuming and often neglected in clinical practice. Elevated Interleukin‐6 (IL‐6) serum levels have been linked to MHE.
Simon Johannes Gairing, Julian Anders, Leonard Kaps, Michael Nagel, Maurice Michel, Wolfgang Maximilian Kremer, Max Hilscher, Peter Robert Galle, Jörn M. Schattenberg, Marcus‐Alexander Wörns, Christian Labenz   +10 more
doaj   +1 more source

P- 91 CHANGES IN EARLY VISUAL PERCEPTION IN PATIENTS WITH MINIMAL HEPATIC ENCEPHALOPATHY

Annals of Hepatology, 2023
Introduction and Objectives: Minimal Hepatic Encephalopathy (MHE) is characterized by very subtle cognitive changes that are diagnosed with the Psychometric hepatic encephalopathy score (PHES) and critical flickering frequency (CFF).
José Luis Pérez Hernández, Diana Montemira Orozco, Christian Israel Hinojosa-Segura, Julieta Zavala Ramírez, Imran Gibran Cruz Reyes, Maria Escobedo Silva, Fatima Higuera-de la Tijera, Daniel Santana Vargas   +7 more
doaj   +1 more source

Minimal Hepatic Encephalopathy in Patients with Cirrhosis Using Psychometric Hepatic Encephalopathy Score Tests

Pakistan Journal of Health Sciences
Minimal hepatic encephalopathy (MHE) is defined as changes in cognitive ability, electrophysiology, and homeostasis of neurotransmission and blood flow in the cerebrum. It is observed in patients with chronic liver disease and cirrhosis who do not have clinical features of overt hepatic encephalopathy.
Humaira Zakir, Amanullah Khokar, Waqas Manzoor, Habiba Aman, Mariam Fatima Waqar, Abdul Majid, Hina Khan   +6 more
openaire   +1 more source

[The Psychometric Score for Hepatic Encephalopathy and the Stroop EncephalApp in the diagnosis of covert hepatic encephalopathy in Cuba].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru, 2021
Introducción: El diagnóstico de la encefalopatía hepática encubierta en pacientes con cirrosis hepática se encuentra en estado de cambio, fundamentalmente en lo que a las pruebas diagnósticas refiere. Objetivo: El objetivo de este estudio fue comparar los resultados diagnósticos de dos test, el Score Psicométrico para Encefalopatía Hepática y el Stroop
openaire   +2 more sources

Fatigue and Cognitive Impairment in Adults With Primary Sclerosing Cholangitis: Results From Concept Elicitation Interviews

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Background and Aims To understand the experience of fatigue and cognitive impairment in adults with symptomatic primary sclerosing cholangitis (PSC) as an essential first step towards developing PSC‐specific symptom measures. Methods Purposeful sampling was used to identify 17 symptomatic adults from the PSC Symptom Assessment Project who met ...
Donna M. Evon, Kaya Merkler, Laura Mkumba, Nicole Lucas, Lauren Wright, Joanne Hatchett, Rachel Gomel, Patrick J. Smith, Sasha Deutsch‐Link, Christopher L. Bowlus, Mark G. Swain, Bryce B. Reeve   +11 more
wiley   +1 more source

Serum levels of neurofilament light chains in the detection of minimal hepatic encephalopathy in patients with liver cirrhosis

Egyptian Liver Journal
Background Minimal hepatic encephalopathy (MHE) is the mildest form of hepatic encephalopathy, often undetected in clinical practice, and reflects central nervous system dysfunction caused by liver disease and/or portosystemic shunting.
Moamena S. Elhamouly, Hosam E. Seleem, Sara M. El- Deeb, Eman M. Arab, Amany Abas Amer   +4 more
doaj   +1 more source