Results 61 to 70 of about 1,141,330 (293)

Longitudinal Behavior Phenotype Hallmarks in RNU4‐2 Syndrome: Implications for Clinical Management

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Pathogenic variants in the non‐coding spliceosomal gene RNU4‐2 underlie ReNU syndrome, one of the most prevalent monogenic causes of neurodevelopmental disorders, accounting for ~0.4% of cases. Despite increasing recognition, little is known about the longitudinal behavioral and neuropsychiatric phenotype of affected individuals. We report two
Paola Francesca Ajmone, Claudia Rigamonti, Francesca Brasca, Donatella Milani, Chiara Ranci Ortigosa, Maria Iascone, Lucrezia Goisis, Annalaura Torella, Maria Antonella Costantino   +8 more
wiley   +1 more source

The effects of alcohol on driver performance in a decision making situation [PDF]

, 1978
The results are reviewed of driving simulator and in-vehicle field test experiments of alcohol effects on driver risk taking. The objective was to investigate changes in risk taking under alcoholic intoxication and relate these changes to effects on ...
Allen, R. W., Hogge, J. R., Schwartz, S. H., Stein, A. C.   +3 more
core   +1 more source

The Phenotypic Spectrum of Sporadic Creutzfeldt‐Jakob Disease Cortical Subtype

Annals of Neurology, EarlyView.
Objective The objective of this study was to characterize the phenotypic spectrum of the rare sporadic Creutzfeldt‐Jakob disease cortical subtype (sCJDMM/MV2C) in a large multicentric autopsy cohort. Methods We evaluated clinical histories, biofluid markers, brain diffusion‐weighted (DW)‐magnetic resonance imaging (MRI), and electroencephalogram (EEG ...
Simone Baiardi, Claudia Marina Vargiu, Brian S. Appleby, Marcelo Barria, Giuseppe Mario Bentivenga, Ignazio Calì, Benedetta Carlà, Mark Cohen, Armin Giese, Jochen Herms, Aino‐Minerva Kortelainen, Anna Ladogana, Angela Mammana, Diane Ritchie, Otto Windl, Sabina Capellari, Piero Parchi   +16 more
wiley   +1 more source

‘SOMS BrainSpace’: A digital serious game for undergraduate neuroscience

Anatomical Sciences Education, EarlyView.
Abstract Neuroanatomy is challenging for many undergraduates, requiring strong visuospatial skills and a deep understanding of complex concepts. This study developed and evaluated SOMS BrainSpace, a digital serious game for neuroanatomy education, using a mixed methods approach.
Anthony Tran, Jin Y. Huang, Craig R. Campbell, Elizabeth M. Hegedus   +3 more
wiley   +1 more source

Multiplex ligation-dependent probe amplification (MLPA) analysis is an effective tool for the detection of novel intragenic PLA2G6 mutations: Implications for molecular diagnosis [PDF]

, 2010
Phospholipase associated neurodegeneration (PLAN) comprises a heterogeneous group of autosomal recessive neurological disorders caused by mutations in the PLA2G6 gene. Direct gene sequencing detects 85% mutations in infantile neuroaxonal dystrophy.
Brady, Angela F, Crompton, Danielle, De Gressi, Susanna, Foster, Kathleen, Hardy, Carol, Hughes, Imelda, Kurian, Manju A, Lunt, Peter, MacPherson, Lesley, Maher, Eamonn R, McDonald, Fiona, Morgan, Neil V, Pike, Michael G, Rehal, Pauline K, Smith, Matthew   +14 more
core   +1 more source

Associating cognitive abilities with naturalistic search behavior

Journal of the Association for Information Science and Technology, Volume 76, Issue 4, Page 665-685, April 2025.
Abstract Differences in cognitive abilities affect search behaviors, but this has mostly been observed in laboratory experiments. There is limited research on how users search for information in real‐world, naturalistic settings and how real‐world search behaviors relate to cognitive abilities.
Tung Vuong, Pritom Kumar Das, Tuukka Ruotsalo   +2 more
wiley   +1 more source

Nilai Pendidikan Islam dalam Qur'an Surah Luqman Ayat 1-19: Tinjauan Kognitif, Afektif, dan Psikomotorik

Al-Musannif, 2019
The main focuses in this study are 1) Islamic educational values contained in QS Luqman/31: 1-9; 2) fostering cognitive, affective, and psychomotor potential according to QS Luqman/31: 1-9; and 3) the results of the development of cognitive, affective ...
Nurhadia Fitri, Mahsyar Idris
doaj   +1 more source

Acute hypoglycemia impairs executive cognitive function in adults with and without type 1 diabetes [PDF]

, 2013
OBJECTIVE: Acute hypoglycemia impairs cognitive function in several domains. Executive cognitive function governs organization of thoughts, prioritization of tasks, and time management.
A. J. Graveling, Albinet, B. M. Frier, Berg, Cox, Elliott, Evans, Geddes, Goel, Gold, Gold, Hardy, Heller, Homack, I. J. Deary, Kerr, Maran, Pedersen-Bjergaard, Salthouse, Sommerfield, Sommerfield, Van der Elst, Warren   +22 more
core   +1 more source

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

British Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia, Huang Xingxing, Jin Lu, Wang Ruwei   +3 more
wiley   +1 more source

Biblical Perspective and Educational Domains in Sex Education: Addressing Gaps in Indonesian Sex Education

Dunamis: Jurnal Teologi dan Pendidikan Kristiani
In Indonesia, sex education is delivered in public high schools as part of the biology curriculum and under the topic of reproductive health. According to the government’s view, when schools teach students properly about reproductive health, they will ...
Esther Idayanti, Jimmy Boaz Oentoro, Frans Silalahi   +2 more
doaj   +1 more source