Results 181 to 190 of about 347,172 (240)

Executive Impairment in Huntington's Disease: Insights From a Systematic Review of the Literature

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
Executive dysfunction in Huntington's disease follows a selective, stage‐dependent pattern, with early deficits in psychomotor speed, cognitive flexibility, inhibition, and working‐memory updating. Progression is associated with broader impairments in planning and attention.
Simone Migliore   +4 more
wiley   +1 more source

Efficacy of Repetitive Transcranial Magnetic Stimulation on Postoperative Delirium in Elderly Patients Undergoing Non‐Cardiac Major Surgery: A Randomized Controlled Trial

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
In this double‐blind randomized controlled trial, preoperative 10‐Hz rTMS targeting the left DLPFC reduced postoperative delirium within 7 days in older adults undergoing elective non‐cardiac surgery compared with sham stimulation and was well tolerated.
Wen‐Bo Gao   +9 more
wiley   +1 more source

Psychometric Properties of the Mixed State Severity Index for Patients With Mood Disorder. [PDF]

open access: yesPsychiatry Investig
Myung W   +18 more
europepmc   +1 more source

Serotonergic Neuromodulation of Natural Products Isoreserpine and Isoreserpiline in Adult Zebrafish: An in Silico and In Vivo Investigation

open access: yesChemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Anxiety is a multidimensional behavioral disorder widely studied in neuroscience due to the involvement of specific neural circuits. Although benzodiazepines are commonly used, their side effects drive the search for new therapeutic alternatives.
Nádia Aguiar Portela Pinheiro   +11 more
wiley   +1 more source

Abnormal temporal prediction relates to psychomotor retardation in major depressive disorder [PDF]

open access: gold
Jianfeng Zhang   +8 more
openalex   +1 more source

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 2, February 2026.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan   +7 more
wiley   +1 more source

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